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Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML.
JCI Insight. 2021 Feb 8;6(3):e142149. doi: 10.1172/jci.insight.142149.
JCI Insight. 2021.
PMID: 33351783
Free PMC article.
Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia.
Tothova Z, Krill-Burger JM, Popova KD, Landers CC, Sievers QL, Yudovich D, Belizaire R, Aster JC, Morgan EA, Tsherniak A, Ebert BL.
Tothova Z, et al. Among authors: landers cc.
Cell Stem Cell. 2017 Oct 5;21(4):547-555.e8. doi: 10.1016/j.stem.2017.07.015.
Cell Stem Cell. 2017.
PMID: 28985529
Free PMC article.
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Ectopic expression of pericentric HSATII RNA results in nuclear RNA accumulation, MeCP2 recruitment, and cell division defects.
Landers CC, Rabeler CA, Ferrari EK, D'Alessandro LR, Kang DD, Malisa J, Bashir SM, Carone DM.
Landers CC, et al.
Chromosoma. 2021 Mar;130(1):75-90. doi: 10.1007/s00412-021-00753-0. Epub 2021 Feb 13.
Chromosoma. 2021.
PMID: 33585981
Free PMC article.
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