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Rapid, point-of-care molecular diagnostics with Cas13.
Agrawal S, Fanton A, Chandrasekaran SS, Charrez B, Escajeda AM, Son S, Mcintosh R, Bhuiya A, de León Derby MD, Switz NA, Armstrong M, Harris AR, Prywes N, Lukarska M, Biering SB, Smock DCJ, Mok A, Knott GJ, Dang Q, Van Dis E, Dugan E, Kim S, Liu TY; IGI Testing Consortium; Harris E, Stanley SA, Lareau LF, Tan MX, Fletcher DA, Doudna JA, Savage DF, Hsu PD. Agrawal S, et al. Among authors: doudna ja. medRxiv [Preprint]. 2021 Apr 5:2020.12.14.20247874. doi: 10.1101/2020.12.14.20247874. medRxiv. 2021. PMID: 33354689 Free PMC article. Preprint.
CRISPR-Cas guides the future of genetic engineering.
Knott GJ, Doudna JA. Knott GJ, et al. Among authors: doudna ja. Science. 2018 Aug 31;361(6405):866-869. doi: 10.1126/science.aat5011. Science. 2018. PMID: 30166482 Free PMC article. Review.
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy.
Fozouni P, Son S, Díaz de León Derby M, Knott GJ, Gray CN, D'Ambrosio MV, Zhao C, Switz NA, Kumar GR, Stephens SI, Boehm D, Tsou CL, Shu J, Bhuiya A, Armstrong M, Harris AR, Chen PY, Osterloh JM, Meyer-Franke A, Joehnk B, Walcott K, Sil A, Langelier C, Pollard KS, Crawford ED, Puschnik AS, Phelps M, Kistler A, DeRisi JL, Doudna JA, Fletcher DA, Ott M. Fozouni P, et al. Among authors: doudna ja. Cell. 2021 Jan 21;184(2):323-333.e9. doi: 10.1016/j.cell.2020.12.001. Epub 2020 Dec 4. Cell. 2021. PMID: 33306959 Free PMC article.
Controlling and enhancing CRISPR systems.
Shivram H, Cress BF, Knott GJ, Doudna JA. Shivram H, et al. Among authors: doudna ja. Nat Chem Biol. 2021 Jan;17(1):10-19. doi: 10.1038/s41589-020-00700-7. Epub 2020 Dec 16. Nat Chem Biol. 2021. PMID: 33328654 Free PMC article. Review.
IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2.
Stahl EC, Tsuchida CA, Hamilton JR, Lin-Shiao E, McDevitt SL, Moehle EA, Witkowsky LB, Tsui CK, Pestal K, Gildea HK, McElroy M, Keller A, Sylvain I, Williams C, Hirsh A, Ciling A, Ehrenberg AJ; IGI SARS-CoV-2 consortium; Urnov FD, Ringeisen BR, Giannikopoulos P, Doudna JA. Stahl EC, et al. Among authors: doudna ja. medRxiv [Preprint]. 2020 Dec 11:2020.12.10.20247338. doi: 10.1101/2020.12.10.20247338. medRxiv. 2020. PMID: 33330883 Free PMC article. Preprint.
385 results