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Rapid, point-of-care molecular diagnostics with Cas13.
Agrawal S, Fanton A, Chandrasekaran SS, Charrez B, Escajeda AM, Son S, Mcintosh R, Bhuiya A, de León Derby MD, Switz NA, Armstrong M, Harris AR, Prywes N, Lukarska M, Biering SB, Smock DCJ, Mok A, Knott GJ, Dang Q, Van Dis E, Dugan E, Kim S, Liu TY; IGI Testing Consortium; Harris E, Stanley SA, Lareau LF, Tan MX, Fletcher DA, Doudna JA, Savage DF, Hsu PD. Agrawal S, et al. Among authors: savage df. medRxiv [Preprint]. 2021 Apr 5:2020.12.14.20247874. doi: 10.1101/2020.12.14.20247874. medRxiv. 2021. PMID: 33354689 Free PMC article. Preprint.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, de León Derby MD, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim SE, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: savage df. medRxiv [Preprint]. 2021 Mar 24:2021.03.19.21253328. doi: 10.1101/2021.03.19.21253328. medRxiv. 2021. PMID: 33791736 Free PMC article. Updated. Preprint.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: savage df. Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. Epub 2021 Aug 5. Nat Chem Biol. 2021. PMID: 34354262 Free PMC article.
Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: savage df. Nat Chem Biol. 2021 Nov;17(11):1210. doi: 10.1038/s41589-021-00882-8. Nat Chem Biol. 2021. PMID: 34616098 Free PMC article. No abstract available.
Rapid detection of SARS-CoV-2 RNA in saliva via Cas13.
Chandrasekaran SS, Agrawal S, Fanton A, Jangid AR, Charrez B, Escajeda AM, Son S, Mcintosh R, Tran H, Bhuiya A, de León Derby MD, Switz NA, Armstrong M, Harris AR, Prywes N, Lukarska M, Biering SB, Smock DCJ, Mok A, Knott GJ, Dang Q, Van Dis E, Dugan E, Kim S, Liu TY; IGI Testing Consortium; Moehle EA, Kogut K, Eskenazi B, Harris E, Stanley SA, Lareau LF, Tan MX, Fletcher DA, Doudna JA, Savage DF, Hsu PD. Chandrasekaran SS, et al. Among authors: savage df. Nat Biomed Eng. 2022 Aug;6(8):944-956. doi: 10.1038/s41551-022-00917-y. Epub 2022 Aug 11. Nat Biomed Eng. 2022. PMID: 35953650 Free PMC article.
Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection.
Armbruster EG, Lee J, Hutchings J, VanderWal AR, Enustun E, Adler BA, Aindow A, Deep A, Rodriguez ZK, Morgan CJ, Ghassemian M, Charles E, Cress BF, Savage DF, Doudna JA, Pogliano K, Corbett KD, Villa E, Pogliano J. Armbruster EG, et al. Among authors: savage df. bioRxiv [Preprint]. 2023 Sep 21:2023.09.20.558163. doi: 10.1101/2023.09.20.558163. bioRxiv. 2023. PMID: 37781618 Free PMC article. Preprint.
Protein design using structure-based residue preferences.
Ding D, Shaw AY, Sinai S, Rollins N, Prywes N, Savage DF, Laub MT, Marks DS. Ding D, et al. Among authors: savage df. Nat Commun. 2024 Feb 22;15(1):1639. doi: 10.1038/s41467-024-45621-4. Nat Commun. 2024. PMID: 38388493 Free PMC article.
76 results