Shoemaker CB - Search Results

1

Delivery of single-domain antibodies into neurons using a chimeric toxin-based platform is therapeutic in mouse models of botulism.

Miyashita SI, Zhang J, Zhang S, Shoemaker CB, Dong M. Miyashita SI, et al. Among authors: shoemaker cb. Sci Transl Med. 2021 Jan 6;13(575):eaaz4197. doi: 10.1126/scitranslmed.aaz4197. Sci Transl Med. 2021. PMID: 33408184

2

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.

Mukherjee J, Tremblay JM, Leysath CE, Ofori K, Baldwin K, Feng X, Bedenice D, Webb RP, Wright PM, Smith LA, Tzipori S, Shoemaker CB. Mukherjee J, et al. Among authors: shoemaker cb. PLoS One. 2012;7(1):e29941. doi: 10.1371/journal.pone.0029941. Epub 2012 Jan 6. PLoS One. 2012. PMID: 22238680 Free PMC article.

3

Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein.

Mukherjee J, Dmitriev I, Debatis M, Tremblay JM, Beamer G, Kashentseva EA, Curiel DT, Shoemaker CB. Mukherjee J, et al. Among authors: shoemaker cb. PLoS One. 2014 Aug 29;9(8):e106422. doi: 10.1371/journal.pone.0106422. eCollection 2014. PLoS One. 2014. PMID: 25170904 Free PMC article.

4

A Diverse Set of Single-domain Antibodies (VHHs) against the Anthrax Toxin Lethal and Edema Factors Provides a Basis for Construction of a Bispecific Agent That Protects against Anthrax Infection.

Vrentas CE, Moayeri M, Keefer AB, Greaney AJ, Tremblay J, O'Mard D, Leppla SH, Shoemaker CB. Vrentas CE, et al. Among authors: shoemaker cb. J Biol Chem. 2016 Oct 7;291(41):21596-21606. doi: 10.1074/jbc.M116.749184. Epub 2016 Aug 18. J Biol Chem. 2016. PMID: 27539858 Free PMC article.

5

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.

Yao G, Lam KH, Weisemann J, Peng L, Krez N, Perry K, Shoemaker CB, Dong M, Rummel A, Jin R. Yao G, et al. Among authors: shoemaker cb. Sci Rep. 2017 Aug 7;7(1):7438. doi: 10.1038/s41598-017-07457-5. Sci Rep. 2017. PMID: 28785006 Free PMC article.

6

Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin.

Huang NJ, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, Dong M, Shoemaker CB, Lodish HF. Huang NJ, et al. Among authors: shoemaker cb. Nat Commun. 2017 Sep 4;8(1):423. doi: 10.1038/s41467-017-00448-0. Nat Commun. 2017. PMID: 28871080 Free PMC article.

7

Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins.

Lam KH, Tremblay JM, Vazquez-Cintron E, Perry K, Ondeck C, Webb RP, McNutt PM, Shoemaker CB, Jin R. Lam KH, et al. Among authors: shoemaker cb. Cell Rep. 2020 Feb 25;30(8):2526-2539.e6. doi: 10.1016/j.celrep.2020.01.107. Cell Rep. 2020. PMID: 32101733 Free PMC article.

8

Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function.

Tremblay JM, Vazquez-Cintron E, Lam KH, Mukherjee J, Bedenice D, Ondeck CA, Conroy MT, Bodt SML, Winner BM, Webb RP, Ichtchenko K, Jin R, McNutt PM, Shoemaker CB. Tremblay JM, et al. Among authors: shoemaker cb. Toxins (Basel). 2020 Sep 24;12(10):611. doi: 10.3390/toxins12100611. Toxins (Basel). 2020. PMID: 32987745 Free PMC article.

9

Neuronal delivery of antibodies has therapeutic effects in animal models of botulism.

McNutt PM, Vazquez-Cintron EJ, Tenezaca L, Ondeck CA, Kelly KE, Mangkhalakhili M, Machamer JB, Angeles CA, Glotfelty EJ, Cika J, Benjumea CH, Whitfield JT, Band PA, Shoemaker CB, Ichtchenko K. McNutt PM, et al. Among authors: shoemaker cb. Sci Transl Med. 2021 Jan 6;13(575):eabd7789. doi: 10.1126/scitranslmed.abd7789. Sci Transl Med. 2021. PMID: 33408188 Free PMC article.

10

Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody.

Lee M, Lu ZH, Shoemaker CB, Tremblay JM, St Croix B, Seaman S, Gonzalez-Pastor R, Kashentseva EA, Dmitriev IP, Curiel DT. Lee M, et al. Among authors: shoemaker cb. J Control Release. 2021 Jun 10;334:106-113. doi: 10.1016/j.jconrel.2021.04.009. Epub 2021 Apr 16. J Control Release. 2021. PMID: 33872627 Free PMC article.

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