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Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth.
Nakagawa R, Toboso-Navasa A, Schips M, Young G, Bhaw-Rosun L, Llorian-Sopena M, Chakravarty P, Sesay AK, Kassiotis G, Meyer-Hermann M, Calado DP. Nakagawa R, et al. Among authors: chakravarty p. Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2016425118. doi: 10.1073/pnas.2016425118. Proc Natl Acad Sci U S A. 2021. PMID: 33419925 Free PMC article.
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.
Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Among authors: chakravarty p. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
Köchl R, Vanes L, Llorian Sopena M, Chakravarty P, Hartweger H, Fountain K, White A, Cowan J, Anderson G, Tybulewicz VL. Köchl R, et al. Among authors: chakravarty p. Elife. 2020 Oct 14;9:e56934. doi: 10.7554/eLife.56934. Elife. 2020. PMID: 33051000 Free PMC article.
Epi-microRNA mediated metabolic reprogramming ensures affinity maturation.
Nakagawa R, Llorian M, Varsani-Brown S, Chakravarty P, Camarillo JM, Barry D, George R, Blackledge NP, Duddy G, Kelleher NL, Klose RJ, Turner M, Calado DP. Nakagawa R, et al. Among authors: chakravarty p. bioRxiv [Preprint]. 2023 Oct 31:2023.07.31.551250. doi: 10.1101/2023.07.31.551250. bioRxiv. 2023. PMID: 37609190 Free PMC article. Preprint.
Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors.
Cabeza-Cabrerizo M, van Blijswijk J, Wienert S, Heim D, Jenkins RP, Chakravarty P, Rogers N, Frederico B, Acton S, Beerling E, van Rheenen J, Clevers H, Schraml BU, Bajénoff M, Gerner M, Germain RN, Sahai E, Klauschen F, Reis e Sousa C. Cabeza-Cabrerizo M, et al. Among authors: chakravarty p. Sci Immunol. 2019 Mar 1;4(33):eaaw1941. doi: 10.1126/sciimmunol.aaw1941. Sci Immunol. 2019. PMID: 30824528 Free PMC article.
229 results