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Targeting the p300/CBP Axis in Lethal Prostate Cancer.
Cancer Discov. 2021 May;11(5):1118-1137. doi: 10.1158/2159-8290.CD-20-0751. Epub 2021 Jan 11.
Cancer Discov. 2021.
PMID: 33431496
Free PMC article.
Cycloaddition of chiral tert-butanesulfinimines with trimethylenemethane.
Procopiou G, Lewis W, Harbottle G, Stockman RA.
Procopiou G, et al.
Org Lett. 2013 Apr 19;15(8):2030-3. doi: 10.1021/ol400720b. Epub 2013 Apr 4.
Org Lett. 2013.
PMID: 23556427
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Two-directional synthesis and biological evaluation of alkaloid 5-epi-cis-275B'.
Procopiou G, Aggarwal P, Newton AF, Richards D, Mellor IR, Harbottle G, Stockman RA.
Procopiou G, et al.
Chem Commun (Camb). 2014 Dec 18;50(97):15355-7. doi: 10.1039/c4cc07287a. Epub 2014 Oct 28.
Chem Commun (Camb). 2014.
PMID: 25348081
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In vitro and in vivo SAR of pyrido[3,4-d]pyramid-4-ylamine based mGluR1 antagonists.
Mantell SJ, Gibson KR, Osborne SA, Maw GN, Rees H, Dodd PG, Greener B, Harbottle GW, Million WA, Poinsard C, England S, Carnell P, Betts AM, Monhemius R, Prime RL.
Mantell SJ, et al. Among authors: harbottle gw.
Bioorg Med Chem Lett. 2009 Apr 15;19(8):2190-4. doi: 10.1016/j.bmcl.2009.02.106. Epub 2009 Mar 3.
Bioorg Med Chem Lett. 2009.
PMID: 19289283
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Structure-activity relationships of novel non-competitive mGluR1 antagonists: a potential treatment for chronic pain.
Owen DR, Dodd PG, Gayton S, Greener BS, Harbottle GW, Mantell SJ, Maw GN, Osborne SA, Rees H, Ringer TJ, Rodriguez-Lens M, Smith GF.
Owen DR, et al. Among authors: harbottle gw.
Bioorg Med Chem Lett. 2007 Jan 15;17(2):486-90. doi: 10.1016/j.bmcl.2006.10.015. Epub 2006 Oct 11.
Bioorg Med Chem Lett. 2007.
PMID: 17064898
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