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Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression.
Dozynkiewicz MA, Jamieson NB, Macpherson I, Grindlay J, van den Berghe PV, von Thun A, Morton JP, Gourley C, Timpson P, Nixon C, McKay CJ, Carter R, Strachan D, Anderson K, Sansom OJ, Caswell PT, Norman JC. Dozynkiewicz MA, et al. Among authors: norman jc. Dev Cell. 2012 Jan 17;22(1):131-45. doi: 10.1016/j.devcel.2011.11.008. Epub 2011 Dec 22. Dev Cell. 2012. PMID: 22197222 Free PMC article.
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
Juin A, Spence HJ, Martin KJ, McGhee E, Neilson M, Cutiongco MFA, Gadegaard N, Mackay G, Fort L, Lilla S, Kalna G, Thomason P, Koh YWH, Norman JC, Insall RH, Machesky LM. Juin A, et al. Among authors: norman jc. Dev Cell. 2019 Nov 18;51(4):431-445.e7. doi: 10.1016/j.devcel.2019.09.018. Epub 2019 Oct 24. Dev Cell. 2019. PMID: 31668663 Free PMC article.
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.
Fetit R, McLaren AS, White M, Mills ML, Falconer J, Cortes-Lavaud X, Gilroy K, Lannagan TRM, Ridgway RA, Nixon C, Naiker V, Njunge R, Clarke CJ, Whyte D, Kirschner K, Jackstadt R, Norman J, Carlin LM, Campbell AD, Sansom OJ, Steele CW. Fetit R, et al. Cancer Res Commun. 2024 Feb 29;4(2):588-606. doi: 10.1158/2767-9764.CRC-23-0319. Cancer Res Commun. 2024. PMID: 38358352 Free PMC article.
Mutant p53 drives invasion by promoting integrin recycling.
Muller PA, Caswell PT, Doyle B, Iwanicki MP, Tan EH, Karim S, Lukashchuk N, Gillespie DA, Ludwig RL, Gosselin P, Cromer A, Brugge JS, Sansom OJ, Norman JC, Vousden KH. Muller PA, et al. Among authors: norman jc. Cell. 2009 Dec 24;139(7):1327-41. doi: 10.1016/j.cell.2009.11.026. Cell. 2009. PMID: 20064378 Free article.
p53 and its mutants in tumor cell migration and invasion.
Muller PA, Vousden KH, Norman JC. Muller PA, et al. Among authors: norman jc. J Cell Biol. 2011 Jan 24;192(2):209-18. doi: 10.1083/jcb.201009059. J Cell Biol. 2011. PMID: 21263025 Free PMC article. Review.
338 results