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Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity.
Gu X, Yang H, Sheng X, Ko YA, Qiu C, Park J, Huang S, Kember R, Judy RL, Park J, Damrauer SM, Nadkarni G, Loos RJF, My VTH, Chaudhary K, Bottinger EP, Paranjpe I, Saha A, Brown C, Akilesh S, Hung AM, Palmer M, Baras A, Overton JD, Reid J, Ritchie M, Rader DJ, Susztak K. Gu X, et al. Sci Transl Med. 2021 Jan 13;13(576):eaaz1458. doi: 10.1126/scitranslmed.aaz1458. Sci Transl Med. 2021. PMID: 33441424 Free PMC article.
Going from acute to chronic kidney injury with FoxO3.
Gu X, Raman A, Susztak K. Gu X, et al. J Clin Invest. 2019 May 6;129(6):2192-2194. doi: 10.1172/JCI128985. eCollection 2019 May 6. J Clin Invest. 2019. PMID: 31063992 Free PMC article.
Loss of proximal tubular transcription factor Krüppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation.
Piret SE, Attallah AA, Gu X, Guo Y, Gujarati NA, Henein J, Zollman A, Hato T, Ma'ayan A, Revelo MP, Dickman KG, Chen CH, Shun CT, Rosenquist TA, He JC, Mallipattu SK. Piret SE, et al. Among authors: gu x. Kidney Int. 2021 Dec;100(6):1250-1267. doi: 10.1016/j.kint.2021.08.031. Epub 2021 Oct 9. Kidney Int. 2021. PMID: 34634362 Free PMC article.
Podocyte-Specific Induction of Krüppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease.
Guo Y, Pace J, Li Z, Ma'ayan A, Wang Z, Revelo MP, Chen E, Gu X, Attalah A, Yang Y, Estrada C, Yang VW, He JC, Mallipattu SK. Guo Y, et al. Among authors: gu x. J Am Soc Nephrol. 2018 Oct;29(10):2529-2545. doi: 10.1681/ASN.2018030324. Epub 2018 Aug 24. J Am Soc Nephrol. 2018. PMID: 30143559 Free PMC article.
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