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p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Cell. 2021 Feb 4;184(3):689-708.e20. doi: 10.1016/j.cell.2020.12.025. Epub 2021 Jan 21.
Cell. 2021.
PMID: 33482083
Free PMC article.
Moving Toward Patient-Tailored Treatment in ALS and FTD: The Potential of Genomic Assessment as a Tool for Biological Discovery and Trial Recruitment.
Broce IJ, Castruita PA, Yokoyama JS.
Broce IJ, et al. Among authors: castruita pa.
Front Neurosci. 2021 Mar 1;15:639078. doi: 10.3389/fnins.2021.639078. eCollection 2021.
Front Neurosci. 2021.
PMID: 33732107
Free PMC article.
Review.
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Genetic, Social, and Lifestyle Drivers of Healthy Aging and Longevity.
Castruita PA, Piña-Escudero SD, Rentería ME, Yokoyama JS.
Castruita PA, et al.
Curr Genet Med Rep. 2022 Sep;10(3):25-34. doi: 10.1007/s40142-022-00205-w. Epub 2022 Sep 26.
Curr Genet Med Rep. 2022.
PMID: 38031561
Free PMC article.
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Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding.
Alegro M, Theofilas P, Nguy A, Castruita PA, Seeley W, Heinsen H, Ushizima DM, Grinberg LT.
Alegro M, et al. Among authors: castruita pa.
J Neurosci Methods. 2017 Apr 15;282:20-33. doi: 10.1016/j.jneumeth.2017.03.002. Epub 2017 Mar 4.
J Neurosci Methods. 2017.
PMID: 28267565
Free PMC article.
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C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Broce IJ, Sirkis DW, Nillo RM, Bonham LW, Lee SE, Miller BL, Castruita PA, Sturm VE, Sugrue LS, Desikan RS, Yokoyama JS.
Broce IJ, et al. Among authors: castruita pa.
Front Neurosci. 2024 Feb 26;18:1258996. doi: 10.3389/fnins.2024.1258996. eCollection 2024.
Front Neurosci. 2024.
PMID: 38469573
Free PMC article.
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