Otonkoski T - Search Results

1

Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress.

Montaser H, Patel KA, Balboa D, Ibrahim H, Lithovius V, Näätänen A, Chandra V, Demir K, Acar S, Ben-Omran T, Colclough K, Locke JM, Wakeling M, Lindahl M, Hattersley AT, Saarimäki-Vire J, Otonkoski T. Montaser H, et al. Among authors: otonkoski t. Diabetes. 2021 Apr;70(4):1006-1018. doi: 10.2337/db20-1174. Epub 2021 Jan 26. Diabetes. 2021. PMID: 33500254 Free PMC article.

2

Maturation of insulin response to glucose during human fetal and neonatal development. Studies with perifusion of pancreatic isletlike cell clusters.

Otonkoski T, Andersson S, Knip M, Simell O. Otonkoski T, et al. Diabetes. 1988 Mar;37(3):286-91. doi: 10.2337/diab.37.3.286. Diabetes. 1988. PMID: 3286329

3

A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland.

Otonkoski T, Ammälä C, Huopio H, Cote GJ, Chapman J, Cosgrove K, Ashfield R, Huang E, Komulainen J, Ashcroft FM, Dunne MJ, Kere J, Thomas PM. Otonkoski T, et al. Diabetes. 1999 Feb;48(2):408-15. doi: 10.2337/diabetes.48.2.408. Diabetes. 1999. PMID: 10334322

4

Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.

Huopio H, Vauhkonen I, Komulainen J, Niskanen L, Otonkoski T, Laakso M. Huopio H, et al. Among authors: otonkoski t. Diabetes Care. 2002 Jan;25(1):101-6. doi: 10.2337/diacare.25.1.101. Diabetes Care. 2002. PMID: 11772909

5

Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release.

Otonkoski T, Kaminen N, Ustinov J, Lapatto R, Meissner T, Mayatepek E, Kere J, Sipilä I. Otonkoski T, et al. Diabetes. 2003 Jan;52(1):199-204. doi: 10.2337/diabetes.52.1.199. Diabetes. 2003. PMID: 12502513

6

Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture.

Gao R, Ustinov J, Pulkkinen MA, Lundin K, Korsgren O, Otonkoski T. Gao R, et al. Among authors: otonkoski t. Diabetes. 2003 Aug;52(8):2007-15. doi: 10.2337/diabetes.52.8.2007. Diabetes. 2003. PMID: 12882917

7

Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron emission tomography.

Otonkoski T, Näntö-Salonen K, Seppänen M, Veijola R, Huopio H, Hussain K, Tapanainen P, Eskola O, Parkkola R, Ekström K, Guiot Y, Rahier J, Laakso M, Rintala R, Nuutila P, Minn H. Otonkoski T, et al. Diabetes. 2006 Jan;55(1):13-8. Diabetes. 2006. PMID: 16380471

8

Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.

Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, Hakonen E, Juntti-Berggren L, Berggren PO, Otonkoski T. Miettinen PJ, et al. Among authors: otonkoski t. Diabetes. 2006 Dec;55(12):3299-308. doi: 10.2337/db06-0413. Diabetes. 2006. PMID: 17130473

9

Activin A and Wnt-dependent specification of human definitive endoderm cells.

Toivonen S, Lundin K, Balboa D, Ustinov J, Tamminen K, Palgi J, Trokovic R, Tuuri T, Otonkoski T. Toivonen S, et al. Among authors: otonkoski t. Exp Cell Res. 2013 Oct 15;319(17):2535-44. doi: 10.1016/j.yexcr.2013.07.007. Epub 2013 Aug 14. Exp Cell Res. 2013. PMID: 23954819

10

MANF is indispensable for the proliferation and survival of pancreatic β cells.

Lindahl M, Danilova T, Palm E, Lindholm P, Võikar V, Hakonen E, Ustinov J, Andressoo JO, Harvey BK, Otonkoski T, Rossi J, Saarma M. Lindahl M, et al. Among authors: otonkoski t. Cell Rep. 2014 Apr 24;7(2):366-375. doi: 10.1016/j.celrep.2014.03.023. Epub 2014 Apr 13. Cell Rep. 2014. PMID: 24726366 Free PMC article.

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