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Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice.
Ryan NM, Hess JA, de Villena FP, Leiby BE, Shimada A, Yu L, Yarmahmoodi A, Petrovsky N, Zhan B, Bottazzi ME, Makepeace BL, Lustigman S, Abraham D. Ryan NM, et al. Among authors: makepeace bl. NPJ Vaccines. 2021 Jan 26;6(1):17. doi: 10.1038/s41541-020-00276-2. NPJ Vaccines. 2021. PMID: 33500417 Free PMC article.
In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.
Tchakouté VL, Graham SP, Jensen SA, Makepeace BL, Nfon CK, Njongmeta LM, Lustigman S, Enyong PA, Tanya VN, Bianco AE, Trees AJ. Tchakouté VL, et al. Among authors: makepeace bl. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5971-6. doi: 10.1073/pnas.0601385103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585501 Free PMC article.
The Onchocerciasis Vaccine for Africa--TOVA--Initiative.
Hotez PJ, Bottazzi ME, Zhan B, Makepeace BL, Klei TR, Abraham D, Taylor DW, Lustigman S. Hotez PJ, et al. Among authors: makepeace bl. PLoS Negl Trop Dis. 2015 Jan 29;9(1):e0003422. doi: 10.1371/journal.pntd.0003422. eCollection 2015 Jan. PLoS Negl Trop Dis. 2015. PMID: 25634641 Free PMC article. No abstract available.
Onchocerca volvulus: The Road from Basic Biology to a Vaccine.
Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Lustigman S, et al. Among authors: makepeace bl. Trends Parasitol. 2018 Jan;34(1):64-79. doi: 10.1016/j.pt.2017.08.011. Epub 2017 Sep 22. Trends Parasitol. 2018. PMID: 28958602 Free PMC article. Review.
Development of a recombinant vaccine against human onchocerciasis.
Abraham D, Graham-Brown J, Carter D, Gray SA, Hess JA, Makepeace BL, Lustigman S. Abraham D, et al. Among authors: makepeace bl. Expert Rev Vaccines. 2021 Nov;20(11):1459-1470. doi: 10.1080/14760584.2021.1977125. Epub 2021 Sep 17. Expert Rev Vaccines. 2021. PMID: 34488533
Co-Administration of Adjuvanted Recombinant Ov-103 and Ov-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine Onchocerca ochengi Infection Model of Human Onchocerciasis.
Luu L, Bah GS, Okah-Nnane NH, Hartley CS, Glover AF, Walsh TR, Lian LY, Zhan B, Bottazzi ME, Abraham D, Petrovsky N, Bayang N, Tangwa B, Ayiseh RB, Mbah GE, Ekale DD, Tanya VN, Lustigman S, Makepeace BL, Graham-Brown J. Luu L, et al. Among authors: makepeace bl. Vaccines (Basel). 2022 May 27;10(6):861. doi: 10.3390/vaccines10060861. Vaccines (Basel). 2022. PMID: 35746469 Free PMC article.
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates.
Ryan NM, Hess JA, Robertson EJ, Tricoche N, Turner C, Davis J, Petrovsky N, Ferguson M, Rinaldi WJ, Wong VM, Shimada A, Zhan B, Bottazzi ME, Makepeace BL, Gray SA, Carter D, Lustigman S, Abraham D. Ryan NM, et al. Among authors: makepeace bl. Vaccines (Basel). 2023 Jul 6;11(7):1212. doi: 10.3390/vaccines11071212. Vaccines (Basel). 2023. PMID: 37515028 Free PMC article.
Characterization of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite.
Rose C, Praulins G, Armstrong SD, Casas-Sanchez A, Davis J, Molyneux G, Yunta C, Stead Z, Prescott M, Perally S, Rutter A, Makepeace BL, La Course EJ, Acosta-Serrano A. Rose C, et al. Among authors: makepeace bl. Parasitology. 2019 Dec;146(14):1773-1784. doi: 10.1017/S0031182019000763. Epub 2019 Jul 3. Parasitology. 2019. PMID: 31190665 Free PMC article.
78 results