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STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
Conde de la Rosa L, Garcia-Ruiz C, Vallejo C, Baulies A, Nuñez S, Monte MJ, Marin JJG, Baila-Rueda L, Cenarro A, Civeira F, Fuster J, Garcia-Valdecasas JC, Ferrer J, Karin M, Ribas V, Fernandez-Checa JC. Conde de la Rosa L, et al. Among authors: vallejo c. J Hepatol. 2021 Jun;74(6):1429-1441. doi: 10.1016/j.jhep.2021.01.028. Epub 2021 Jan 27. J Hepatol. 2021. PMID: 33515644 Free PMC article.
The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading.
Baulies A, Montero J, Matías N, Insausti N, Terrones O, Basañez G, Vallejo C, Conde de La Rosa L, Martinez L, Robles D, Morales A, Abian J, Carrascal M, Machida K, Kumar DBU, Tsukamoto H, Kaplowitz N, Garcia-Ruiz C, Fernández-Checa JC. Baulies A, et al. Among authors: vallejo c. Redox Biol. 2018 Apr;14:164-177. doi: 10.1016/j.redox.2017.08.022. Epub 2017 Sep 14. Redox Biol. 2018. PMID: 28942194 Free PMC article.
Enhanced tumorigenicity by mitochondrial DNA mild mutations.
Cruz-Bermúdez A, Vallejo CG, Vicente-Blanco RJ, Gallardo ME, Fernández-Moreno MÁ, Quintanilla M, Garesse R. Cruz-Bermúdez A, et al. Oncotarget. 2015 May 30;6(15):13628-43. doi: 10.18632/oncotarget.3698. Oncotarget. 2015. PMID: 25909222 Free PMC article.
287 results