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Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.
Neff RA, Wang M, Vatansever S, Guo L, Ming C, Wang Q, Wang E, Horgusluoglu-Moloch E, Song WM, Li A, Castranio EL, Tcw J, Ho L, Goate A, Fossati V, Noggle S, Gandy S, Ehrlich ME, Katsel P, Schadt E, Cai D, Brennand KJ, Haroutunian V, Zhang B. Neff RA, et al. Among authors: wang e, wang m, wang q. Sci Adv. 2021 Jan 6;7(2):eabb5398. doi: 10.1126/sciadv.abb5398. Print 2021 Jan. Sci Adv. 2021. PMID: 33523961 Free PMC article.
Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility.
Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, Liu X, Doyle MA, Scobie KN, Sun HS, Neve RL, Geschwind D, Dong Y, Shen L, Zhang B, Nestler EJ. Bagot RC, et al. Among authors: wang j, wang m. Neuron. 2016 Jun 1;90(5):969-83. doi: 10.1016/j.neuron.2016.04.015. Epub 2016 May 12. Neuron. 2016. PMID: 27181059 Free PMC article.
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.
Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B. Wang M, et al. Genome Med. 2016 Nov 1;8(1):104. doi: 10.1186/s13073-016-0355-3. Genome Med. 2016. PMID: 27799057 Free PMC article.
Directed Differentiation of Human Pluripotent Stem Cells to Microglia.
Douvaras P, Sun B, Wang M, Kruglikov I, Lallos G, Zimmer M, Terrenoire C, Zhang B, Gandy S, Schadt E, Freytes DO, Noggle S, Fossati V. Douvaras P, et al. Among authors: wang m. Stem Cell Reports. 2017 Jun 6;8(6):1516-1524. doi: 10.1016/j.stemcr.2017.04.023. Epub 2017 May 18. Stem Cell Reports. 2017. PMID: 28528700 Free PMC article.
Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
Haure-Mirande JV, Audrain M, Fanutza T, Kim SH, Klein WL, Glabe C, Readhead B, Dudley JT, Blitzer RD, Wang M, Zhang B, Schadt EE, Gandy S, Ehrlich ME. Haure-Mirande JV, et al. Among authors: wang m. Acta Neuropathol. 2017 Nov;134(5):769-788. doi: 10.1007/s00401-017-1737-3. Epub 2017 Jun 13. Acta Neuropathol. 2017. PMID: 28612290 Free PMC article.
An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells.
Tcw J, Wang M, Pimenova AA, Bowles KR, Hartley BJ, Lacin E, Machlovi SI, Abdelaal R, Karch CM, Phatnani H, Slesinger PA, Zhang B, Goate AM, Brennand KJ. Tcw J, et al. Among authors: wang m. Stem Cell Reports. 2017 Aug 8;9(2):600-614. doi: 10.1016/j.stemcr.2017.06.018. Epub 2017 Jul 27. Stem Cell Reports. 2017. PMID: 28757165 Free PMC article.
A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE. Peters LA, et al. Among authors: wang m. Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038/ng.3947. Epub 2017 Sep 11. Nat Genet. 2017. PMID: 28892060 Free PMC article.
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