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Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.
Neff RA, Wang M, Vatansever S, Guo L, Ming C, Wang Q, Wang E, Horgusluoglu-Moloch E, Song WM, Li A, Castranio EL, Tcw J, Ho L, Goate A, Fossati V, Noggle S, Gandy S, Ehrlich ME, Katsel P, Schadt E, Cai D, Brennand KJ, Haroutunian V, Zhang B. Neff RA, et al. Among authors: zhang b. Sci Adv. 2021 Jan 6;7(2):eabb5398. doi: 10.1126/sciadv.abb5398. Print 2021 Jan. Sci Adv. 2021. PMID: 33523961 Free PMC article.
A systems biology approach to drug discovery.
Zhu J, Zhang B, Schadt EE. Zhu J, et al. Among authors: zhang b. Adv Genet. 2008;60:603-35. doi: 10.1016/S0065-2660(07)00421-X. Adv Genet. 2008. PMID: 18358334 Review.
Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.
Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Readhead B, et al. Among authors: zhang b. Mol Psychiatry. 2016 Aug;21(8):1099-111. doi: 10.1038/mp.2015.167. Epub 2015 Nov 10. Mol Psychiatry. 2016. PMID: 26552589 Free PMC article.
Multiscale Embedded Gene Co-expression Network Analysis.
Song WM, Zhang B. Song WM, et al. Among authors: zhang b. PLoS Comput Biol. 2015 Nov 30;11(11):e1004574. doi: 10.1371/journal.pcbi.1004574. eCollection 2015 Nov. PLoS Comput Biol. 2015. PMID: 26618778 Free PMC article.
Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.
Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Readhead B, et al. Among authors: zhang b. Mol Psychiatry. 2016 Aug;21(8):1153-4. doi: 10.1038/mp.2015.215. Epub 2016 Jan 19. Mol Psychiatry. 2016. PMID: 26782051 Free PMC article. No abstract available.
Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility.
Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, Liu X, Doyle MA, Scobie KN, Sun HS, Neve RL, Geschwind D, Dong Y, Shen L, Zhang B, Nestler EJ. Bagot RC, et al. Among authors: zhang b. Neuron. 2016 Jun 1;90(5):969-83. doi: 10.1016/j.neuron.2016.04.015. Epub 2016 May 12. Neuron. 2016. PMID: 27181059 Free PMC article.
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