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Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer.
Jin Y, Qu S, Tesikova M, Wang L, Kristian A, Mælandsmo GM, Kong H, Zhang T, Jerónimo C, Teixeira MR, Yuca E, Tekedereli I, Gorgulu K, Alpay N, Sood AK, Lopez-Berestein G, Danielsen HE, Ozpolat B, Saatcioglu F. Jin Y, et al. Among authors: ozpolat b. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2572-81. doi: 10.1073/pnas.1304318110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798432 Free PMC article.
Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer.
Tekedereli I, Alpay SN, Akar U, Yuca E, Ayugo-Rodriguez C, Han HD, Sood AK, Lopez-Berestein G, Ozpolat B. Tekedereli I, et al. Among authors: ozpolat b. Mol Ther Nucleic Acids. 2013 Sep 10;2(9):e121. doi: 10.1038/mtna.2013.45. Mol Ther Nucleic Acids. 2013. PMID: 24022053 Free PMC article.
Antagonism of tumoral prolactin receptor promotes autophagy-related cell death.
Wen Y, Zand B, Ozpolat B, Szczepanski MJ, Lu C, Yuca E, Carroll AR, Alpay N, Bartholomeusz C, Tekedereli I, Kang Y, Rupaimoole R, Pecot CV, Dalton HJ, Hernandez A, Lokshin A, Lutgendorf SK, Liu J, Hittelman WN, Chen WY, Lopez-Berestein G, Szajnik M, Ueno NT, Coleman RL, Sood AK. Wen Y, et al. Among authors: ozpolat b. Cell Rep. 2014 Apr 24;7(2):488-500. doi: 10.1016/j.celrep.2014.03.009. Epub 2014 Apr 3. Cell Rep. 2014. PMID: 24703838 Free PMC article.
181 results