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Page 1
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations.
Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, Cheon JH, Datta LW, Daryani NE, Ellul P, Esaki M, Fuyuno Y, McGovern DPB, Haritunians T, Hong M, Juyal G, Jung ES, Kubo M, Kugathasan S, Lenz TL, Leslie S, Malekzadeh R, Midha V, Motyer A, Ng SC, Okou DT, Raychaudhuri S, Schembri J, Schreiber S, Song K, Sood A, Takahashi A, Torres EA, Umeno J, Alizadeh BZ, Weersma RK, Wong SH, Yamazaki K, Karlsen TH, Rioux JD, Brant SR; MAAIS Recruitment Center; Franke A; International IBD Genetics Consortium. Degenhardt F, et al. Among authors: leslie s. Hum Mol Genet. 2021 Apr 27;30(5):356-369. doi: 10.1093/hmg/ddab017. Hum Mol Genet. 2021. PMID: 33555323 Free PMC article.
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S; International Inflammatory Bowel Disease Genetics Consortium; Australia and New Zealand IBDGC; Belgium IBD Genetics Consortium; Italian Group for IBD Genetic Consortium; NIDDK Inflammatory Bowel Disease Genetics Consortium; United Kingdom IBDGC; Wellcome Trust Case Control Consortium; Quebec IBD Genetics Consortium; Daly MJ, Van Steen K, Duerr RH, Barrett JC, McGovern DP, Schumm LP, Traherne JA, Carrington MN, Kosmoliaptsis V, Karlsen TH, Franke A, Rioux JD. Goyette P, et al. Among authors: leslie s. Nat Genet. 2015 Feb;47(2):172-9. doi: 10.1038/ng.3176. Epub 2015 Jan 5. Nat Genet. 2015. PMID: 25559196 Free PMC article.
Imputation of KIR Types from SNP Variation Data.
Vukcevic D, Traherne JA, Næss S, Ellinghaus E, Kamatani Y, Dilthey A, Lathrop M, Karlsen TH, Franke A, Moffatt M, Cookson W, Trowsdale J, McVean G, Sawcer S, Leslie S. Vukcevic D, et al. Among authors: leslie s. Am J Hum Genet. 2015 Oct 1;97(4):593-607. doi: 10.1016/j.ajhg.2015.09.005. Am J Hum Genet. 2015. PMID: 26430804 Free PMC article.
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G; International MHC and Autoimmunity Genetics Network; Langefeld CD, Noble JA, Rioux JD, Seldin MF; Systemic Lupus Erythematosus Genetics Consortium; Criswell LA, Vyse TJ. Morris DL, et al. Am J Hum Genet. 2012 Nov 2;91(5):778-93. doi: 10.1016/j.ajhg.2012.08.026. Epub 2012 Oct 18. Am J Hum Genet. 2012. PMID: 23084292 Free PMC article.
Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis.
Ahn R, Vukcevic D, Motyer A, Nititham J, Squire DM, Hollenbach JA, Norman PJ, Ellinghaus E, Nair RP, Tsoi LC, Oksenberg J, Foerster J, Lieb W, Weidinger S, Franke A, Elder JT, Jorgenson E, Leslie S, Liao W. Ahn R, et al. Among authors: leslie s. Front Immunol. 2021 Jun 11;12:684326. doi: 10.3389/fimmu.2021.684326. eCollection 2021. Front Immunol. 2021. PMID: 34177931 Free PMC article.
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.
International MHC and Autoimmunity Genetics Network; Rioux JD, Goyette P, Vyse TJ, Hammarström L, Fernando MM, Green T, De Jager PL, Foisy S, Wang J, de Bakker PI, Leslie S, McVean G, Padyukov L, Alfredsson L, Annese V, Hafler DA, Pan-Hammarström Q, Matell R, Sawcer SJ, Compston AD, Cree BA, Mirel DB, Daly MJ, Behrens TW, Klareskog L, Gregersen PK, Oksenberg JR, Hauser SL. International MHC and Autoimmunity Genetics Network, et al. Among authors: leslie s. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18680-5. doi: 10.1073/pnas.0909307106. Epub 2009 Oct 21. Proc Natl Acad Sci U S A. 2009. PMID: 19846760 Free PMC article.
Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1.
Martino DJ, Ashley S, Koplin J, Ellis J, Saffery R, Dharmage SC, Gurrin L, Matheson MC, Kalb B, Marenholz I, Beyer K, Lee YA, Hong X, Wang X, Vukcevic D, Motyer A, Leslie S, Allen KJ, Ferreira MA. Martino DJ, et al. Among authors: leslie s. Clin Exp Allergy. 2017 Feb;47(2):217-223. doi: 10.1111/cea.12863. Epub 2017 Jan 11. Clin Exp Allergy. 2017. PMID: 27883235
Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.
Pappas DJ, Lizee A, Paunic V, Beutner KR, Motyer A, Vukcevic D, Leslie S, Biesiada J, Meller J, Taylor KD, Zheng X, Zhao LP, Gourraud PA, Hollenbach JA, Mack SJ, Maiers M. Pappas DJ, et al. Among authors: leslie s. Pharmacogenomics J. 2018 May 22;18(3):367-376. doi: 10.1038/tpj.2017.7. Epub 2017 Apr 25. Pharmacogenomics J. 2018. PMID: 28440342 Free PMC article.
Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis.
Hanson AL; International Genetics of Ankylosing Spondylitis Consortium; Vukcevic D, Leslie S, Harris J, Lê Cao KA, Kenna TJ, Brown MA. Hanson AL, et al. Among authors: leslie s. PLoS Genet. 2020 Aug 17;16(8):e1008906. doi: 10.1371/journal.pgen.1008906. eCollection 2020 Aug. PLoS Genet. 2020. PMID: 32804949 Free PMC article.
727 results