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Sensitive tracking of circulating viral RNA through all stages of SARS-CoV-2 infection.
Huang Z, Ning B, Yang HS, Youngquist BM, Niu A, Lyon CJ, Beddingfield BJ, Fears AC, Monk CH, Murrell AE, Bilton SJ, Linhuber JP, Norton EB, Dietrich ML, Yee J, Lai W, Scott JW, Yin XM, Rappaport J, Robinson JE, Saba NS, Roy CJ, Zwezdaryk KJ, Zhao Z, Hu TY. Huang Z, et al. Among authors: rappaport j. J Clin Invest. 2021 Apr 1;131(7):e146031. doi: 10.1172/JCI146031. J Clin Invest. 2021. PMID: 33561010 Free PMC article. Clinical Trial.
A smartphone-read ultrasensitive and quantitative saliva test for COVID-19.
Ning B, Yu T, Zhang S, Huang Z, Tian D, Lin Z, Niu A, Golden N, Hensley K, Threeton B, Lyon CJ, Yin XM, Roy CJ, Saba NS, Rappaport J, Wei Q, Hu TY. Ning B, et al. Among authors: rappaport j. Sci Adv. 2021 Jan 8;7(2):eabe3703. doi: 10.1126/sciadv.abe3703. Print 2021 Jan. Sci Adv. 2021. PMID: 33310733 Free PMC article.
Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection.
Han K, Blair RV, Iwanaga N, Liu F, Russell-Lodrigue KE, Qin Z, Midkiff CC, Golden NA, Doyle-Meyers LA, Kabir ME, Chandler KE, Cutrera KL, Ren M, Monjure CJ, Lehmicke G, Fischer T, Beddingfield B, Wanek AG, Birnbaum A, Maness NJ, Roy CJ, Datta PK, Rappaport J, Kolls JK, Qin X. Han K, et al. Among authors: rappaport j. Am J Respir Cell Mol Biol. 2021 Jan;64(1):79-88. doi: 10.1165/rcmb.2020-0354OC. Am J Respir Cell Mol Biol. 2021. PMID: 32991819 Free PMC article.
Acute Respiratory Distress in Aged, SARS-CoV-2-Infected African Green Monkeys but Not Rhesus Macaques.
Blair RV, Vaccari M, Doyle-Meyers LA, Roy CJ, Russell-Lodrigue K, Fahlberg M, Monjure CJ, Beddingfield B, Plante KS, Plante JA, Weaver SC, Qin X, Midkiff CC, Lehmicke G, Golden N, Threeton B, Penney T, Allers C, Barnes MB, Pattison M, Datta PK, Maness NJ, Birnbaum A, Fischer T, Bohm RP, Rappaport J. Blair RV, et al. Among authors: rappaport j. Am J Pathol. 2021 Feb;191(2):274-282. doi: 10.1016/j.ajpath.2020.10.016. Epub 2020 Nov 7. Am J Pathol. 2021. PMID: 33171111 Free PMC article.
SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro.
Liu F, Han K, Blair R, Kenst K, Qin Z, Upcin B, Wörsdörfer P, Midkiff CC, Mudd J, Belyaeva E, Milligan NS, Rorison TD, Wagner N, Bodem J, Dölken L, Aktas BH, Vander Heide RS, Yin XM, Kolls JK, Roy CJ, Rappaport J, Ergün S, Qin X. Liu F, et al. Among authors: rappaport j. Front Cell Infect Microbiol. 2021 Jul 6;11:701278. doi: 10.3389/fcimb.2021.701278. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34307198 Free PMC article.
Effective Prophylaxis of COVID-19 in Rhesus Macaques Using a Combination of Two Parenterally-Administered SARS-CoV-2 Neutralizing Antibodies.
Beddingfield BJ, Maness NJ, Fears AC, Rappaport J, Aye PP, Russell-Lodrigue K, Doyle-Meyers LA, Blair RV, Carias AM, Madden PJ, Redondo RL, Gao H, Montefiori D, Hope TJ, Roy CJ. Beddingfield BJ, et al. Among authors: rappaport j. Front Cell Infect Microbiol. 2021 Nov 18;11:753444. doi: 10.3389/fcimb.2021.753444. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34869063 Free PMC article.
Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates.
Rutkai I, Mayer MG, Hellmers LM, Ning B, Huang Z, Monjure CJ, Coyne C, Silvestri R, Golden N, Hensley K, Chandler K, Lehmicke G, Bix GJ, Maness NJ, Russell-Lodrigue K, Hu TY, Roy CJ, Blair RV, Bohm R, Doyle-Meyers LA, Rappaport J, Fischer T. Rutkai I, et al. Among authors: rappaport j. Nat Commun. 2022 Apr 1;13(1):1745. doi: 10.1038/s41467-022-29440-z. Nat Commun. 2022. PMID: 35365631 Free PMC article.
Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates.
Fahlberg MD, Blair RV, Doyle-Meyers LA, Midkiff CC, Zenere G, Russell-Lodrigue KE, Monjure CJ, Haupt EH, Penney TP, Lehmicke G, Threeton BM, Golden N, Datta PK, Roy CJ, Bohm RP, Maness NJ, Fischer T, Rappaport J, Vaccari M. Fahlberg MD, et al. Among authors: rappaport j. Nat Commun. 2020 Nov 27;11(1):6078. doi: 10.1038/s41467-020-19967-4. Nat Commun. 2020. PMID: 33247138 Free PMC article.
The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease.
Melton A, Doyle-Meyers LA, Blair RV, Midkiff C, Melton HJ, Russell-Lodrigue K, Aye PP, Schiro F, Fahlberg M, Szeltner D, Spencer S, Beddingfield BJ, Goff K, Golden N, Penney T, Picou B, Hensley K, Chandler KE, Plante JA, Plante KS, Weaver SC, Roy CJ, Hoxie JA, Gao H, Montefiori DC, Mankowski JL, Bohm RP, Rappaport J, Maness NJ. Melton A, et al. Among authors: rappaport j. PLoS Pathog. 2021 Dec 20;17(12):e1010162. doi: 10.1371/journal.ppat.1010162. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34929014 Free PMC article.
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.
Arunachalam PS, Feng Y, Ashraf U, Hu M, Walls AC, Edara VV, Zarnitsyna VI, Aye PP, Golden N, Miranda MC, Green KWM, Threeton BM, Maness NJ, Beddingfield BJ, Bohm RP, Scheuermann SE, Goff K, Dufour J, Russell-Lodrigue K, Kepl E, Fiala B, Wrenn S, Ravichandran R, Ellis D, Carter L, Rogers K, Shirreff LM, Ferrell DE, Deb Adhikary NR, Fontenot J, Hammond HL, Frieman M, Grifoni A, Sette A, O'Hagan DT, Van Der Most R, Rappuoli R, Villinger F, Kleanthous H, Rappaport J, Suthar MS, Veesler D, Wang TT, King NP, Pulendran B. Arunachalam PS, et al. Among authors: rappaport j. Sci Transl Med. 2022 Aug 17;14(658):eabq4130. doi: 10.1126/scitranslmed.abq4130. Epub 2022 Aug 17. Sci Transl Med. 2022. PMID: 35976993 Free PMC article.
293 results