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Page 1
The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians.
Sun H, Lin M, Russell EM, Minster RL, Chan TF, Dinh BL, Naseri T, Reupena MS, Lum-Jones A; Samoan Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group; Cheng I, Wilkens LR, Le Marchand L, Haiman CA, Chiang CWK. Sun H, et al. Among authors: russell em. PLoS Genet. 2021 Feb 11;17(2):e1009273. doi: 10.1371/journal.pgen.1009273. eCollection 2021 Feb. PLoS Genet. 2021. PMID: 33571193 Free PMC article.
A missense variant in CREBRF is associated with taller stature in Samoans.
Carlson JC, Rosenthal SL, Russell EM, Hawley NL, Sun G, Cheng H, Naseri T, Reupena MS, Tuitele J, Deka R, McGarvey ST, Weeks DE, Minster RL. Carlson JC, et al. Among authors: russell em. Am J Hum Biol. 2020 Nov;32(6):e23414. doi: 10.1002/ajhb.23414. Epub 2020 Mar 19. Am J Hum Biol. 2020. PMID: 32190945 Free PMC article.
CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand.
Russell EM, Carlson JC, Krishnan M, Hawley NL, Sun G, Cheng H, Naseri T, Reupena MS, Viali S, Tuitele J, Major TJ, Miljkovic I, Merriman TR, Deka R, Weeks DE, McGarvey ST, Minster RL. Russell EM, et al. BMJ Open Diabetes Res Care. 2022 Feb;10(1):e002275. doi: 10.1136/bmjdrc-2021-002275. BMJ Open Diabetes Res Care. 2022. PMID: 35144939 Free PMC article.
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Wainschtein P, Jain D, Zheng Z; TOPMed Anthropometry Working Group; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, Albert CM, Roden D, Chasman DI, Darbar D, Lloyd-Jones DM, Arnett DK, Regan EA, Boerwinkle E, Rotter JI, O'Connell JR, Yanek LR, de Andrade M, Allison MA, McDonald MN, Chung MK, Fornage M, Chami N, Smith NL, Ellinor PT, Vasan RS, Mathias RA, Loos RJF, Rich SS, Lubitz SA, Heckbert SR, Redline S, Guo X, Chen Y-I, Laurie CA, Hernandez RD, McGarvey ST, Goddard ME, Laurie CC, North KE, Lange LA, Weir BS, Yengo L, Yang J, Visscher PM. Wainschtein P, et al. Nat Genet. 2022 Mar;54(3):263-273. doi: 10.1038/s41588-021-00997-7. Epub 2022 Mar 7. Nat Genet. 2022. PMID: 35256806 Free PMC article.
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.
DiCorpo D, Gaynor SM, Russell EM, Westerman KE, Raffield LM, Majarian TD, Wu P, Sarnowski C, Highland HM, Jackson A, Hasbani NR, de Vries PS, Brody JA, Hidalgo B, Guo X, Perry JA, O'Connell JR, Lent S, Montasser ME, Cade BE, Jain D, Wang H, D'Oliveira Albanus R, Varshney A, Yanek LR, Lange L, Palmer ND, Almeida M, Peralta JM, Aslibekyan S, Baldridge AS, Bertoni AG, Bielak LF, Chen CS, Chen YI, Choi WJ, Goodarzi MO, Floyd JS, Irvin MR, Kalyani RR, Kelly TN, Lee S, Liu CT, Loesch D, Manson JE, Minster RL, Naseri T, Pankow JS, Rasmussen-Torvik LJ, Reiner AP, Reupena MS, Selvin E, Smith JA, Weeks DE, Xu H, Yao J, Zhao W, Parker S, Alonso A, Arnett DK, Blangero J, Boerwinkle E, Correa A, Cupples LA, Curran JE, Duggirala R, He J, Heckbert SR, Kardia SLR, Kim RW, Kooperberg C, Liu S, Mathias RA, McGarvey ST, Mitchell BD, Morrison AC, Peyser PA, Psaty BM, Redline S, Shuldiner AR, Taylor KD, Vasan RS, Viaud-Martinez KA, Florez JC, Wilson JG, Sladek R, Rich SS, Rotter JI, Lin X, Dupuis J, Meigs JB, Wessel J, Manning AK. DiCorpo D, et al. Among authors: russell em. Commun Biol. 2022 Jul 28;5(1):756. doi: 10.1038/s42003-022-03702-4. Commun Biol. 2022. PMID: 35902682 Free PMC article.
The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans.
Hawley NL, Duckham RL, Carlson JC, Naseri T, Reupena MS, Lameko V, Pomer A, Wetzel A, Selu M, Lupematisila V, Unasa F, Vesi L, Fatu T, Unasa S, Faasalele-Savusa K, Rivara AC, Russell E, Delany JP, Viali S, Kershaw EE, Minster RL, Weeks DE, McGarvey ST. Hawley NL, et al. Obesity (Silver Spring). 2022 Dec;30(12):2468-2476. doi: 10.1002/oby.23559. Epub 2022 Oct 25. Obesity (Silver Spring). 2022. PMID: 36284436 Free PMC article.
A stop-gain variant in BTNL9 is associated with atherogenic lipid profiles.
Carlson JC, Krishnan M, Rosenthal SL, Russell EM, Zhang JZ, Hawley NL, Moors J, Cheng H, Dalbeth N, de Zoysa JR, Watson H, Qasim M, Murphy R, Naseri T, Reupena MS, Viali S, Stamp LK, Tuitele J, Kershaw EE, Deka R, McGarvey ST, Merriman TR, Weeks DE, Minster RL. Carlson JC, et al. Among authors: russell em. HGG Adv. 2022 Oct 12;4(1):100155. doi: 10.1016/j.xhgg.2022.100155. eCollection 2023 Jan 12. HGG Adv. 2022. PMID: 36340932 Free PMC article.
Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations.
Krishnan M, Phipps-Green A, Russell EM, Major TJ, Cadzow M, Stamp LK, Dalbeth N, Hindmarsh JH, Qasim M, Watson H, Liu S, Carlson JC, Minster RL, Hawley NL, Naseri T, Reupena MS, Deka R, McGarvey ST, Merriman TR, Murphy R, Weeks DE. Krishnan M, et al. Among authors: russell em. J Hum Genet. 2023 Jul;68(7):463-468. doi: 10.1038/s10038-023-01141-5. Epub 2023 Mar 2. J Hum Genet. 2023. PMID: 36864286 Free PMC article.
A Polynesian-specific missense CETP variant alters the lipid profile.
Moors J, Krishnan M, Sumpter N, Takei R, Bixley M, Cadzow M, Major TJ, Phipps-Green A, Topless R, Merriman M, Rutledge M, Morgan B, Carlson JC, Zhang JZ, Russell EM, Sun G, Cheng H, Weeks DE, Naseri T, Reupena MS, Viali S, Tuitele J, Hawley NL, Deka R, McGarvey ST, de Zoysa J, Murphy R, Dalbeth N, Stamp L, Taumoepeau M, King F, Wilcox P, Rapana N, McCormick S, Minster RL, Merriman TR, Leask M. Moors J, et al. Among authors: russell em. HGG Adv. 2023 May 8;4(3):100204. doi: 10.1016/j.xhgg.2023.100204. eCollection 2023 Jul 13. HGG Adv. 2023. PMID: 37250494 Free PMC article.
70 results