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GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility.
Eriksson D, Røyrvik EC, Aranda-Guillén M, Berger AH, Landegren N, Artaza H, Hallgren Å, Grytaas MA, Ström S, Bratland E, Botusan IR, Oftedal BE, Breivik L, Vaudel M, Helgeland Ø, Falorni A, Jørgensen AP, Hulting AL, Svartberg J, Ekwall O, Fougner KJ, Wahlberg J, Nedrebø BG, Dahlqvist P; Norwegian Addison Registry Study Group; Swedish Addison Registry Study Group; Knappskog PM, Wolff ASB, Bensing S, Johansson S, Kämpe O, Husebye ES. Eriksson D, et al. Among authors: botusan ir. Nat Commun. 2021 Feb 11;12(1):959. doi: 10.1038/s41467-021-21015-8. Nat Commun. 2021. PMID: 33574239 Free PMC article.
A polygenic risk score to help discriminate primary adrenal insufficiency of different etiologies.
Aranda-Guillén M, Røyrvik EC, Fletcher-Sandersjöö S, Artaza H, Botusan IR, Grytaas MA, Hallgren Å, Breivik L, Pettersson M, Jørgensen AP, Lindstrand A, Vogt E; Norwegian Addison Registry Study Group, The Swedish Addison Registry Study Group; Husebye ES, Kämpe O, Wolff ASB, Bensing S, Johansson S, Eriksson D. Aranda-Guillén M, et al. Among authors: botusan ir. J Intern Med. 2023 Jul;294(1):96-109. doi: 10.1111/joim.13649. Epub 2023 May 21. J Intern Med. 2023. PMID: 37151110
High-resolution daily profiles of tissue adrenal steroids by portable automated collection.
Upton TJ, Zavala E, Methlie P, Kämpe O, Tsagarakis S, Øksnes M, Bensing S, Vassiliadi DA, Grytaas MA, Botusan IR, Ueland G, Berinder K, Simunkova K, Balomenaki M, Margaritopoulos D, Henne N, Crossley R, Russell G, Husebye ES, Lightman SL. Upton TJ, et al. Among authors: botusan ir. Sci Transl Med. 2023 Jun 21;15(701):eadg8464. doi: 10.1126/scitranslmed.adg8464. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343084
HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism.
Narayanan S, Eliasson Angelstig S, Xu C, Grünler J, Zhao A, Zhu W, Xu Landén N, Ståhle M, Zhang J, Ivan M, Maltesen RG, Botusan IR, Rajamand Ekberg N, Zheng X, Catrina SB. Narayanan S, et al. Among authors: botusan ir. Commun Biol. 2020 Dec 14;3(1):768. doi: 10.1038/s42003-020-01495-y. Commun Biol. 2020. PMID: 33318569 Free PMC article.
Desmopressin increases IGF-binding protein-1 in humans.
Catrina SB, Rotarus R, Botusan IR, Coculescu M, Brismar K. Catrina SB, et al. Among authors: botusan ir. Eur J Endocrinol. 2008 Apr;158(4):479-82. doi: 10.1530/EJE-07-0662. Eur J Endocrinol. 2008. PMID: 18362294 Clinical Trial.
Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice.
Botusan IR, Sunkari VG, Savu O, Catrina AI, Grünler J, Lindberg S, Pereira T, Ylä-Herttuala S, Poellinger L, Brismar K, Catrina SB. Botusan IR, et al. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19426-31. doi: 10.1073/pnas.0805230105. Epub 2008 Dec 4. Proc Natl Acad Sci U S A. 2008. PMID: 19057015 Free PMC article.
23 results