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Deficiency of innate and acquired immunity caused by an IKBKB mutation.
Pannicke U, Baumann B, Fuchs S, Henneke P, Rensing-Ehl A, Rizzi M, Janda A, Hese K, Schlesier M, Holzmann K, Borte S, Laux C, Rump EM, Rosenberg A, Zelinski T, Schrezenmeier H, Wirth T, Ehl S, Schroeder ML, Schwarz K. Pannicke U, et al. Among authors: holzmann k. N Engl J Med. 2013 Dec 26;369(26):2504-14. doi: 10.1056/NEJMoa1309199. N Engl J Med. 2013. PMID: 24369075 Free article.
Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation.
Sunami Y, Leithäuser F, Gul S, Fiedler K, Güldiken N, Espenlaub S, Holzmann KH, Hipp N, Sindrilaru A, Luedde T, Baumann B, Wissel S, Kreppel F, Schneider M, Scharffetter-Kochanek K, Kochanek S, Strnad P, Wirth T. Sunami Y, et al. Among authors: holzmann kh. Hepatology. 2012 Sep;56(3):1117-28. doi: 10.1002/hep.25711. Epub 2012 Jul 10. Hepatology. 2012. PMID: 22407857
Peripheral monocytes are functionally altered and invade the CNS in ALS patients.
Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf WP, Grozdanov V, Thiemann M, Fundel-Clemes K, Freischmidt A, Holzmann K, Strobel B, Weydt P, Witting A, Thal DR, Helferich AM, Hengerer B, Gottschalk KE, Hill O, Kluge M, Ludolph AC, Danzer KM, Weishaupt JH. Zondler L, et al. Among authors: holzmann k. Acta Neuropathol. 2016 Sep;132(3):391-411. doi: 10.1007/s00401-016-1548-y. Epub 2016 Feb 24. Acta Neuropathol. 2016. PMID: 26910103
213 results