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Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma.
Ene-Obong A, Clear AJ, Watt J, Wang J, Fatah R, Riches JC, Marshall JF, Chin-Aleong J, Chelala C, Gribben JG, Ramsay AG, Kocher HM. Ene-Obong A, et al. Among authors: clear aj. Gastroenterology. 2013 Nov;145(5):1121-32. doi: 10.1053/j.gastro.2013.07.025. Epub 2013 Jul 25. Gastroenterology. 2013. PMID: 23891972 Free PMC article.
Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations.
Riches JC, O'Donovan CJ, Kingdon SJ, McClanahan F, Clear AJ, Neuberg DS, Werner L, Croce CM, Ramsay AG, Rassenti LZ, Kipps TJ, Gribben JG. Riches JC, et al. Among authors: clear aj. Blood. 2014 Jun 26;123(26):4101-10. doi: 10.1182/blood-2014-01-552307. Epub 2014 May 14. Blood. 2014. PMID: 24829201 Free PMC article. Clinical Trial.
PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma.
D'Avola A, Legrave N, Tajan M, Chakravarty P, Shearer RL, King HW, Kluckova K, Cheung EC, Clear AJ, Gunawan AS, Zhang L, James LK, MacRae JI, Gribben JG, Calado DP, Vousden KH, Riches JC. D'Avola A, et al. Among authors: clear aj. J Clin Invest. 2024 Feb 15;134(4):e179917. doi: 10.1172/JCI179917. J Clin Invest. 2024. PMID: 38357928 Free PMC article. No abstract available.
51 results