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Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients.
Buffart TE, van den Oord RAHM, van den Berg A, Hilhorst R, Bastiaensen N, Pruijt HFM, van den Brule A, Nooijen P, Labots M, de Goeij-de Haas RR, Dekker H, Piersma SR, Pham TV, van der Leij T, de Wijn R, Ruijtenbeek R, Jiménez CR, Verheul HMW. Buffart TE, et al. Among authors: dekker h. Clin Proteomics. 2021 Feb 18;18(1):8. doi: 10.1186/s12014-020-09306-6. Clin Proteomics. 2021. PMID: 33602116 Free PMC article.
Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.
Gotink KJ, Broxterman HJ, Labots M, de Haas RR, Dekker H, Honeywell RJ, Rudek MA, Beerepoot LV, Musters RJ, Jansen G, Griffioen AW, Assaraf YG, Pili R, Peters GJ, Verheul HM. Gotink KJ, et al. Among authors: dekker h. Clin Cancer Res. 2011 Dec 1;17(23):7337-46. doi: 10.1158/1078-0432.CCR-11-1667. Epub 2011 Oct 6. Clin Cancer Res. 2011. PMID: 21980135 Free PMC article.
Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer.
van der Mijn JC, Sol N, Mellema W, Jimenez CR, Piersma SR, Dekker H, Schutte LM, Smit EF, Broxterman HJ, Skog J, Tannous BA, Wurdinger T, Verheul HM. van der Mijn JC, et al. Among authors: dekker h. J Extracell Vesicles. 2014 Dec 8;3:25657. doi: 10.3402/jev.v3.25657. eCollection 2014. J Extracell Vesicles. 2014. PMID: 25491250 Free PMC article.
Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature.
Gotink KJ, Broxterman HJ, Honeywell RJ, Dekker H, de Haas RR, Miles KM, Adelaiye R, Griffioen AW, Peters GJ, Pili R, Verheul HM. Gotink KJ, et al. Among authors: dekker h. Oncoscience. 2014 Dec 15;1(12):844-53. doi: 10.18632/oncoscience.106. eCollection 2014. Oncoscience. 2014. PMID: 25621299 Free PMC article.
Sunitinib activates Axl signaling in renal cell cancer.
van der Mijn JC, Broxterman HJ, Knol JC, Piersma SR, De Haas RR, Dekker H, Pham TV, Van Beusechem VW, Halmos B, Mier JW, Jiménez CR, Verheul HM. van der Mijn JC, et al. Among authors: dekker h. Int J Cancer. 2016 Jun 15;138(12):3002-10. doi: 10.1002/ijc.30022. Epub 2016 Mar 1. Int J Cancer. 2016. PMID: 26815723 Free article.
Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab.
Walraven M, Homs MYV, van der Veldt AAM, Dekker H, Koldenhof J, Honeywell R, Barendrecht A, Sebastian SAE, Parr N, Koekman AC, Voest EE, Roest M, Korporaal SJA, Verheul HMW. Walraven M, et al. Among authors: dekker h. Angiogenesis. 2018 May;21(2):325-334. doi: 10.1007/s10456-018-9598-5. Epub 2018 Mar 12. Angiogenesis. 2018. PMID: 29532289 Free PMC article.
292 results