Hilhorst R - Search Results

1

Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients.

Buffart TE, van den Oord RAHM, van den Berg A, Hilhorst R, Bastiaensen N, Pruijt HFM, van den Brule A, Nooijen P, Labots M, de Goeij-de Haas RR, Dekker H, Piersma SR, Pham TV, van der Leij T, de Wijn R, Ruijtenbeek R, Jiménez CR, Verheul HMW. Buffart TE, et al. Among authors: hilhorst r. Clin Proteomics. 2021 Feb 18;18(1):8. doi: 10.1186/s12014-020-09306-6. Clin Proteomics. 2021. PMID: 33602116 Free PMC article.

2

Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A.

Hilhorst R, Houkes L, van den Berg A, Ruijtenbeek R. Hilhorst R, et al. Anal Biochem. 2009 Apr 15;387(2):150-61. doi: 10.1016/j.ab.2009.01.022. Epub 2009 Jan 21. Anal Biochem. 2009. PMID: 19344656

3

Development of selective bisubstrate-based inhibitors against protein kinase C (PKC) isozymes by using dynamic peptide microarrays.

Poot AJ, van Ameijde J, Slijper M, van den Berg A, Hilhorst R, Ruijtenbeek R, Rijkers DT, Liskamp RM. Poot AJ, et al. Among authors: hilhorst r. Chembiochem. 2009 Aug 17;10(12):2042-51. doi: 10.1002/cbic.200900199. Chembiochem. 2009. PMID: 19618415

4

Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation.

Sanz A, Ungureanu D, Pekkala T, Ruijtenbeek R, Touw IP, Hilhorst R, Silvennoinen O. Sanz A, et al. Among authors: hilhorst r. PLoS One. 2011 Apr 18;6(4):e18522. doi: 10.1371/journal.pone.0018522. PLoS One. 2011. PMID: 21533163 Free PMC article.

5

Protein kinase activity profiling of postmortem human brain tissue.

Hoozemans JJ, Hilhorst R, Ruijtenbeek R, Rozemuller AJ, van der Vies SM. Hoozemans JJ, et al. Among authors: hilhorst r. Neurodegener Dis. 2012;10(1-4):46-8. doi: 10.1159/000335914. Epub 2012 Feb 16. Neurodegener Dis. 2012. PMID: 22343098

6

Peptide microarrays for profiling of serine/threonine kinase activity of recombinant kinases and lysates of cells and tissue samples.

Hilhorst R, Houkes L, Mommersteeg M, Musch J, van den Berg A, Ruijtenbeek R. Hilhorst R, et al. Methods Mol Biol. 2013;977:259-71. doi: 10.1007/978-1-62703-284-1_21. Methods Mol Biol. 2013. PMID: 23436369

7

AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and dose dependent reduction of tyrosine kinase activity in acute myeloid leukemia.

Eriksson A, Kalushkova A, Jarvius M, Hilhorst R, Rickardson L, Kultima HG, de Wijn R, Hovestad L, Fryknäs M, Öberg F, Larsson R, Parrow V, Höglund M. Eriksson A, et al. Among authors: hilhorst r. Biochem Pharmacol. 2014 Jan 15;87(2):284-91. doi: 10.1016/j.bcp.2013.10.022. Epub 2013 Nov 4. Biochem Pharmacol. 2014. PMID: 24200998 Free article. Clinical Trial.

8

The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains.

Sanz Sanz A, Niranjan Y, Hammarén H, Ungureanu D, Ruijtenbeek R, Touw IP, Silvennoinen O, Hilhorst R. Sanz Sanz A, et al. Among authors: hilhorst r. Biochim Biophys Acta. 2014 Oct;1844(10):1835-41. doi: 10.1016/j.bbapap.2014.07.003. Epub 2014 Aug 7. Biochim Biophys Acta. 2014. PMID: 25107665

9

Peptide Microarrays for Real-Time Kinetic Profiling of Tyrosine Phosphatase Activity of Recombinant Phosphatases and Phosphatases in Lysates of Cells or Tissue Samples.

Hovestad-Bijl L, van Ameijde J, Pijnenburg D, Hilhorst R, Liskamp R, Ruijtenbeek R. Hovestad-Bijl L, et al. Among authors: hilhorst r. Methods Mol Biol. 2016;1447:67-78. doi: 10.1007/978-1-4939-3746-2_4. Methods Mol Biol. 2016. PMID: 27514800

10

Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles.

Sawada T, Hilhorst R, Rangarajan S, Yoshida M, Tanabe Y, Tamura K, Kinoshita T, Shimoyama T, van Beuningen R, Ruijtenbeek R, Tsuda H, Koizumi F. Sawada T, et al. Among authors: hilhorst r. Oncotarget. 2018 Sep 28;9(76):34229-34239. doi: 10.18632/oncotarget.26026. eCollection 2018 Sep 28. Oncotarget. 2018. PMID: 30344939 Free PMC article.

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