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Patient-derived xenografts and organoids model therapy response in prostate cancer.
Karkampouna S, La Manna F, Benjak A, Kiener M, De Menna M, Zoni E, Grosjean J, Klima I, Garofoli A, Bolis M, Vallerga A, Theurillat JP, De Filippo MR, Genitsch V, Keller D, Booij TH, Stirnimann CU, Eng K, Sboner A, Ng CKY, Piscuoglio S, Gray PC, Spahn M, Rubin MA, Thalmann GN, Kruithof-de Julio M. Karkampouna S, et al. Among authors: grosjean j. Nat Commun. 2021 Feb 18;12(1):1117. doi: 10.1038/s41467-021-21300-6. Nat Commun. 2021. PMID: 33602919 Free PMC article.
Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer.
Zoni E, Astrologo L, Ng CKY, Piscuoglio S, Melsen J, Grosjean J, Klima I, Chen L, Snaar-Jagalska EB, Flanagan K, van der Pluijm G, Kloen P, Cecchini MG, Kruithof-de Julio M, Thalmann GN. Zoni E, et al. Among authors: grosjean j. Mol Cancer Res. 2019 May;17(5):1049-1062. doi: 10.1158/1541-7786.MCR-18-1220. Epub 2019 Feb 11. Mol Cancer Res. 2019. PMID: 30745464 Free article.
ALK1Fc Suppresses the Human Prostate Cancer Growth in in Vitro and in Vivo Preclinical Models.
Astrologo L, Zoni E, Karkampouna S, Gray PC, Klima I, Grosjean J, Goumans MJ, Hawinkels LJAC, van der Pluijm G, Spahn M, Thalmann GN, Ten Dijke P, Kruithof-de Julio M. Astrologo L, et al. Among authors: grosjean j. Front Cell Dev Biol. 2017 Dec 5;5:104. doi: 10.3389/fcell.2017.00104. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 29259971 Free PMC article.
CRIPTO promotes an aggressive tumour phenotype and resistance to treatment in hepatocellular carcinoma.
Karkampouna S, van der Helm D, Gray PC, Chen L, Klima I, Grosjean J, Burgmans MC, Farina-Sarasqueta A, Snaar-Jagalska EB, Stroka DM, Terracciano L, van Hoek B, Schaapherder AF, Osanto S, Thalmann GN, Verspaget HW, Coenraad MJ, Kruithof-de Julio M. Karkampouna S, et al. Among authors: grosjean j. J Pathol. 2018 Jul;245(3):297-310. doi: 10.1002/path.5083. Epub 2018 May 9. J Pathol. 2018. PMID: 29604056
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling.
Pettersen K, Andersen S, Degen S, Tadini V, Grosjean J, Hatakeyama S, Tesfahun AN, Moestue S, Kim J, Nonstad U, Romundstad PR, Skorpen F, Sørhaug S, Amundsen T, Grønberg BH, Strasser F, Stephens N, Hoem D, Molven A, Kaasa S, Fearon K, Jacobi C, Bjørkøy G. Pettersen K, et al. Among authors: grosjean j. Sci Rep. 2017 May 17;7(1):2046. doi: 10.1038/s41598-017-02088-2. Sci Rep. 2017. PMID: 28515477 Free PMC article.
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