Tobe K - Search Results

1

Genome-wide association studies identify two novel loci conferring susceptibility to diabetic retinopathy in Japanese patients with type 2 diabetes.

Imamura M, Takahashi A, Matsunami M, Horikoshi M, Iwata M, Araki SI, Toyoda M, Susarla G, Ahn J, Park KH, Kong J, Moon S, Sobrin L; International Diabetic Retinopathy and Genetics CONsortium (iDRAGON); Yamauchi T, Tobe K, Maegawa H, Kadowaki T, Maeda S. Imamura M, et al. Among authors: tobe k. Hum Mol Genet. 2021 May 17;30(8):716-726. doi: 10.1093/hmg/ddab044. Hum Mol Genet. 2021. PMID: 33607655 Free PMC article.

2

Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor.

Odawara M, Kadowaki T, Yamamoto R, Shibasaki Y, Tobe K, Accili D, Bevins C, Mikami Y, Matsuura N, Akanuma Y, et al. Odawara M, et al. Among authors: tobe k. Science. 1989 Jul 7;245(4913):66-8. doi: 10.1126/science.2544998. Science. 1989. PMID: 2544998

3

Ornithine decarboxylase induction during liver regeneration in IRS-1-deficient mice.

Furusaka A, Nishiyama M, Nishimaki H, Ogasawara Y, Tamemoto H, Yamauchi T, Tobe K, Kadowaki T, Tanaka T. Furusaka A, et al. Among authors: tobe k. Biochem Biophys Res Commun. 1995 Nov 2;216(1):284-90. doi: 10.1006/bbrc.1995.2622. Biochem Biophys Res Commun. 1995. PMID: 7488102

4

Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1.

Tobe K, Tamemoto H, Yamauchi T, Aizawa S, Yazaki Y, Kadowaki T. Tobe K, et al. J Biol Chem. 1995 Mar 17;270(11):5698-701. doi: 10.1074/jbc.270.11.5698. J Biol Chem. 1995. PMID: 7534300 Free article.

Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited growth retardation and mild insulin resistance, suggesting the presence of IRS-1-independent pathway that partially substitutes for IRS-1 i …

Recently, we generated mice with a targeted disruption of the insulin receptor substrate-1 (IRS-1) gene and demonstrated that they exhibited …

5

[The role of phosphorylation cascade in insulin action].

Tobe K, Ueki K, Tamemoto H, Kaburagi Y, Honda R, Kadowaki T. Tobe K, et al. Nihon Rinsho. 1994 Oct;52(10):2673-85. Nihon Rinsho. 1994. PMID: 7983797 Review. Japanese.

6

A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA.

Kadowaki T, Kadowaki H, Mori Y, Tobe K, Sakuta R, Suzuki Y, Tanabe Y, Sakura H, Awata T, Goto Y, et al. Kadowaki T, et al. Among authors: tobe k. N Engl J Med. 1994 Apr 7;330(14):962-8. doi: 10.1056/NEJM199404073301403. N Engl J Med. 1994. PMID: 8121460 Free article.

7

Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice.

Yamauchi T, Tobe K, Tamemoto H, Ueki K, Kaburagi Y, Yamamoto-Honda R, Takahashi Y, Yoshizawa F, Aizawa S, Akanuma Y, Sonenberg N, Yazaki Y, Kadowaki T. Yamauchi T, et al. Among authors: tobe k. Mol Cell Biol. 1996 Jun;16(6):3074-84. doi: 10.1128/MCB.16.6.3074. Mol Cell Biol. 1996. PMID: 8649419 Free PMC article.

8

Csk enhances insulin-stimulated dephosphorylation of focal adhesion proteins.

Tobe K, Sabe H, Yamamoto T, Yamauchi T, Asai S, Kaburagi Y, Tamemoto H, Ueki K, Kimura H, Akanuma Y, Yazaki Y, Hanafusa H, Kadowaki T. Tobe K, et al. Mol Cell Biol. 1996 Sep;16(9):4765-72. doi: 10.1128/MCB.16.9.4765. Mol Cell Biol. 1996. PMID: 8756634 Free PMC article.

9

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 and identification of insulin receptor substrate-2.

Kadowaki T, Tamemoto H, Tobe K, Terauchi Y, Ueki K, Kaburagi Y, Yamauchi T, Satoh S, Sekihara H, Aizawa S, Yazaki Y. Kadowaki T, et al. Among authors: tobe k. Diabet Med. 1996 Sep;13(9 Suppl 6):S103-8. Diabet Med. 1996. PMID: 8894493

10

Signal transduction mechanism of insulin and insulin-like growth factor-1.

Kadowaki T, Tobe K, Honda-Yamamoto R, Tamemoto H, Kaburagi Y, Momomura K, Ueki K, Takahashi Y, Yamauchi T, Akanuma Y, Yazaki Y. Kadowaki T, et al. Among authors: tobe k. Endocr J. 1996 Oct;43 Suppl:S33-41. doi: 10.1507/endocrj.43.suppl_s33. Endocr J. 1996. PMID: 9076340 Free article. Review.

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