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A Novel SNCA A30G Mutation Causes Familial Parkinson's Disease.
Liu H, Koros C, Strohäker T, Schulte C, Bozi M, Varvaresos S, Ibáñez de Opakua A, Simitsi AM, Bougea A, Voumvourakis K, Maniati M, Papageorgiou SG, Hauser AK, Becker S, Zweckstetter M, Stefanis L, Gasser T. Liu H, et al. Among authors: ibanez de opakua a. Mov Disord. 2021 Jul;36(7):1624-1633. doi: 10.1002/mds.28534. Epub 2021 Feb 22. Mov Disord. 2021. PMID: 33617693
Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer.
Zhao J, DiGiacomo V, Ferreras-Gutierrez M, Dastjerdi S, Ibáñez de Opakua A, Park JC, Luebbers A, Chen Q, Beeler A, Blanco FJ, Garcia-Marcos M. Zhao J, et al. Among authors: ibanez de opakua a. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2213140120. doi: 10.1073/pnas.2213140120. Epub 2023 Apr 25. Proc Natl Acad Sci U S A. 2023. PMID: 37098067 Free PMC article.
Molecular Basis of Small-Molecule Binding to α-Synuclein.
Robustelli P, Ibanez-de-Opakua A, Campbell-Bezat C, Giordanetto F, Becker S, Zweckstetter M, Pan AC, Shaw DE. Robustelli P, et al. Among authors: ibanez de opakua a. J Am Chem Soc. 2022 Feb 16;144(6):2501-2510. doi: 10.1021/jacs.1c07591. Epub 2022 Feb 7. J Am Chem Soc. 2022. PMID: 35130691 Free PMC article.
A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity.
Kumar ST, Mahul-Mellier AL, Hegde RN, Rivière G, Moons R, Ibáñez de Opakua A, Magalhães P, Rostami I, Donzelli S, Sobott F, Zweckstetter M, Lashuel HA. Kumar ST, et al. Among authors: ibanez de opakua a. Sci Adv. 2022 Apr 29;8(17):eabn0044. doi: 10.1126/sciadv.abn0044. Epub 2022 Apr 29. Sci Adv. 2022. PMID: 35486726 Free PMC article.
25 results