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Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off-label in the first wave of COVID-19.
Delaunois A, Abernathy M, Anderson WD, Beattie KA, Chaudhary KW, Coulot J, Gryshkova V, Hebeisen S, Holbrook M, Kramer J, Kuryshev Y, Leishman D, Lushbough I, Passini E, Redfern WS, Rodriguez B, Rossman EI, Trovato C, Wu C, Valentin JP. Delaunois A, et al. Among authors: redfern ws. Clin Transl Sci. 2021 May;14(3):1133-1146. doi: 10.1111/cts.13011. Epub 2021 Apr 9. Clin Transl Sci. 2021. PMID: 33620150 Free PMC article.
Proarrhythmia liability assessment and the comprehensive in vitro Proarrhythmia Assay (CiPA): An industry survey on current practice.
Authier S, Pugsley MK, Koerner JE, Fermini B, Redfern WS, Valentin JP, Vargas HM, Leishman DJ, Correll K, Curtis MJ. Authier S, et al. Among authors: redfern ws. J Pharmacol Toxicol Methods. 2017 Jul;86:34-43. doi: 10.1016/j.vascn.2017.02.021. Epub 2017 Feb 20. J Pharmacol Toxicol Methods. 2017. PMID: 28223123 Free article.
An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation.
Authier S, Abernathy MM, Correll K, Chui RW, Dalton J, Foley CM, Friedrichs GS, Koerner JE, Kallman MJ, Pannirselvam M, Redfern WS, Urmaliya V, Valentin JP, Wisialowski T, Zabka TS, Pugsley MK. Authier S, et al. Among authors: redfern ws. Int J Toxicol. 2020 Jul/Aug;39(4):274-293. doi: 10.1177/1091581820921338. Epub 2020 May 14. Int J Toxicol. 2020. PMID: 32406289
The Diplomate in Safety Pharmacology (DSP) certification scheme.
Authier S, Curtis MJ, Soloviev M, Redfern WS, Kallman MJ, Hamlin RL, Leishman DJ, Valentin JP, Koerner JE, Vargas HM, Botchway A, Correll K, Pugsley MK. Authier S, et al. Among authors: redfern ws. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:1-4. doi: 10.1016/j.vascn.2015.04.008. Epub 2015 May 8. J Pharmacol Toxicol Methods. 2015. PMID: 25959882
Safety pharmacology--a progressive approach.
Redfern WS, Wakefield ID, Prior H, Pollard CE, Hammond TG, Valentin JP. Redfern WS, et al. Fundam Clin Pharmacol. 2002 Jun;16(3):161-73. doi: 10.1046/j.1472-8206.2002.00098.x. Fundam Clin Pharmacol. 2002. PMID: 12165064
The application of in vitro methods to safety pharmacology.
Wakefield ID, Pollard C, Redfern WS, Hammond TG, Valentin JP. Wakefield ID, et al. Among authors: redfern ws. Fundam Clin Pharmacol. 2002 Jun;16(3):209-18. doi: 10.1046/j.1472-8206.2002.00099.x. Fundam Clin Pharmacol. 2002. PMID: 12165068 Review.
46 results