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Rapid Tuberculosis Diagnostics Including Molecular First- and Second-Line Resistance Testing Based on a Novel Microfluidic DNA Extraction Cartridge.
Beutler M, Homann AR, Mihalic M, Plesnik S, Niebling L, Eckart M, Allerheiligen V, Czurratis D, Maharjan B, Shrestha B, Parpieva N, Turaev L, Sayfutdinov Z, Hofmann-Thiel S, Grasse W, Metzger-Boddien C, Paust N, Hoffmann H. Beutler M, et al. Among authors: plesnik s. J Mol Diagn. 2021 May;23(5):643-650. doi: 10.1016/j.jmoldx.2021.02.004. Epub 2021 Feb 23. J Mol Diagn. 2021. PMID: 33636391 Free article.
A pre-clinical validation plan to evaluate analytical sensitivities of molecular diagnostics such as BD MAX MDR-TB, Xpert MTB/Rif Ultra and FluoroType MTB.
Beutler M, Plesnik S, Mihalic M, Olbrich L, Heinrich N, Schumacher S, Lindner M, Koch I, Grasse W, Metzger-Boddien C, Hofmann-Thiel S, Hoffmann H. Beutler M, et al. Among authors: plesnik s. PLoS One. 2020 Jan 7;15(1):e0227215. doi: 10.1371/journal.pone.0227215. eCollection 2020. PLoS One. 2020. PMID: 31910223 Free PMC article.
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: A genotypic analysis.
Walker TM, Miotto P, Köser CU, Fowler PW, Knaggs J, Iqbal Z, Hunt M, Chindelevitch L, Farhat M, Cirillo DM, Comas I, Posey J, Omar SV, Peto TE, Suresh A, Uplekar S, Laurent S, Colman RE, Nathanson CM, Zignol M, Walker AS; CRyPTIC Consortium; Seq&Treat Consortium; Crook DW, Ismail N, Rodwell TC. Walker TM, et al. Lancet Microbe. 2022 Apr;3(4):e265-e273. doi: 10.1016/S2666-5247(21)00301-3. Lancet Microbe. 2022. PMID: 35373160 Free PMC article.
A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.
Fowler PW, Wright C, Spiers H, Zhu T, Baeten EML, Hoosdally SW, Gibertoni Cruz AL, Roohi A, Kouchaki S, Walker TM, Peto TEA, Miller G, Lintott C, Clifton D, Crook DW, Walker AS; Zooniverse Volunteer Community; CRyPTIC Consortium. Fowler PW, et al. Elife. 2022 May 19;11:e75046. doi: 10.7554/eLife.75046. Elife. 2022. PMID: 35588296 Free PMC article.
Investigating resistance in clinical Mycobacterium tuberculosis complex isolates with genomic and phenotypic antimicrobial susceptibility testing: a multicentre observational study.
Finci I, Albertini A, Merker M, Andres S, Bablishvili N, Barilar I, Cáceres T, Crudu V, Gotuzzo E, Hapeela N, Hoffmann H, Hoogland C, Kohl TA, Kranzer K, Mantsoki A, Maurer FP, Nicol MP, Noroc E, Plesnik S, Rodwell T, Ruhwald M, Savidge T, Salfinger M, Streicher E, Tukvadze N, Warren R, Zemanay W, Zurek A, Niemann S, Denkinger CM. Finci I, et al. Among authors: plesnik s. Lancet Microbe. 2022 Sep;3(9):e672-e682. doi: 10.1016/S2666-5247(22)00116-1. Epub 2022 Jul 27. Lancet Microbe. 2022. PMID: 35907429 Free PMC article.
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Sonnenkalb L, Carter JJ, Spitaleri A, Iqbal Z, Hunt M, Malone KM, Utpatel C, Cirillo DM, Rodrigues C, Nilgiriwala KS, Fowler PW, Merker M, Niemann S; Comprehensive Resistance Prediction for Tuberculosis: an International Consortium. Sonnenkalb L, et al. Lancet Microbe. 2023 May;4(5):e358-e368. doi: 10.1016/S2666-5247(23)00002-2. Epub 2023 Mar 29. Lancet Microbe. 2023. PMID: 37003285 Free PMC article.
Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis.
Rancoita PMV, Cugnata F, Gibertoni Cruz AL, Borroni E, Hoosdally SJ, Walker TM, Grazian C, Davies TJ, Peto TEA, Crook DW, Fowler PW, Cirillo DM; CRyPTIC Consortiumfor the CRyPTIC Consortiumfor the CRyPTIC Consortium. Rancoita PMV, et al. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e00344-18. doi: 10.1128/AAC.00344-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29941636 Free PMC article.
15 results