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Multistage designs in the genomic era: providing balance in complex disease studies.
Dubé MP, Schmidt S, Hauser E, Darabi H, Li J, Barhdadi A, Wang X, Sha Q, Zhang Z, Wang T, Aschard H, Guedj M, Rohlfs R, Anderson A, Taylor C, Mirea L, Nickolov R, Milanov V, Yang HC, Song Y, Sinha R. Dubé MP, et al. Among authors: aschard h. Genet Epidemiol. 2007;31 Suppl 1(Suppl 1):S118-23. doi: 10.1002/gepi.20288. Genet Epidemiol. 2007. PMID: 18046769 Free PMC article. Review.
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, Pooley KA, Dennis J, Michailidou K, Turman C, Soucy P, Lemaçon A, Lush M, Tyrer JP, Ghoussaini M, Moradi Marjaneh M, Jiang X, Agata S, Aittomäki K, Alonso MR, Andrulis IL, Anton-Culver H, Antonenkova NN, Arason A, Arndt V, Aronson KJ, Arun BK, Auber B, Auer PL, Azzollini J, Balmaña J, Barkardottir RB, Barrowdale D, Beeghly-Fadiel A, Benitez J, Bermisheva M, Białkowska K, Blanco AM, Blomqvist C, Blot W, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Borg A, Bosse K, Brauch H, Brenner H, Briceno I, Brock IW, Brooks-Wilson A, Brüning T, Burwinkel B, Buys SS, Cai Q, Caldés T, Caligo MA, Camp NJ, Campbell I, Canzian F, Carroll JS, Carter BD, Castelao JE, Chiquette J, Christiansen H, Chung WK, Claes KBM, Clarke CL; GEMO Study Collaborators; EMBRACE Collaborators; Collée JM, Cornelissen S, Couch FJ, Cox A, Cross SS, Cybulski C, Czene K, Daly MB, de la Hoya M, Devilee P, Diez O, Ding YC, Dite GS, Domchek SM, Dörk T, Dos-Santos-Silva I, Droit A, Dubois S, Dumont M, Duran M, Durcan L, Dwek M, Eccles DM, Engel C, Eriksson M, Evans DG, Fasching PA, Fletcher O, Floris G, Flyger H, Foretova L, Foulkes WD, Friedman E, Fritschi L, … See abstract for full author list ➔ Fachal L, et al. Among authors: aschard h. Nat Genet. 2020 Jan;52(1):56-73. doi: 10.1038/s41588-019-0537-1. Epub 2020 Jan 7. Nat Genet. 2020. PMID: 31911677 Free PMC article.
Multitrait GWAS to connect disease variants and biological mechanisms.
Julienne H, Laville V, McCaw ZR, He Z, Guillemot V, Lasry C, Ziyatdinov A, Nerin C, Vaysse A, Lechat P, Ménager H, Le Goff W, Dube MP, Kraft P, Ionita-Laza I, Vilhjálmsson BJ, Aschard H. Julienne H, et al. Among authors: aschard h. PLoS Genet. 2021 Aug 30;17(8):e1009713. doi: 10.1371/journal.pgen.1009713. eCollection 2021 Aug. PLoS Genet. 2021. PMID: 34460823 Free PMC article.
Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank.
Kim J, Kennedy Neary MT, Aschard H, Palakkamanil MM, Do R, Wiggs JL, Khawaja AP, Pasquale LR, Kang JH; International Glaucoma Genetics Consortium (IGGC), UK Biobank Eye and Vision Consortium, and Modifiable Risk Factors for Glaucoma Collaboration. Kim J, et al. Among authors: aschard h. Invest Ophthalmol Vis Sci. 2022 May 2;63(5):31. doi: 10.1167/iovs.63.5.31. Invest Ophthalmol Vis Sci. 2022. PMID: 35612836 Free PMC article.
Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative. COVID-19 Host Genetics Initiative. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8. Nature. 2021. PMID: 34237774 Free PMC article.
Making the Most of Clumping and Thresholding for Polygenic Scores.
Privé F, Vilhjálmsson BJ, Aschard H, Blum MGB. Privé F, et al. Among authors: aschard h. Am J Hum Genet. 2019 Dec 5;105(6):1213-1221. doi: 10.1016/j.ajhg.2019.11.001. Epub 2019 Nov 21. Am J Hum Genet. 2019. PMID: 31761295 Free PMC article.
125 results