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Page 1
PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment.
Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. Israel E, et al. Among authors: akuthota p. J Allergy Clin Immunol. 2021 May;147(5):1594-1601. doi: 10.1016/j.jaci.2021.01.037. Epub 2021 Mar 2. J Allergy Clin Immunol. 2021. PMID: 33667479 Free PMC article.
Novel Treatments for Airway Disease.
Wechsler ME, Akuthota P, Khoury P. Wechsler ME, et al. Among authors: akuthota p. N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. N Engl J Med. 2017. PMID: 28792869 No abstract available.
Novel Treatments for Airway Disease.
Wechsler ME, Akuthota P, Khoury P. Wechsler ME, et al. Among authors: akuthota p. N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. N Engl J Med. 2017. PMID: 28812971 No abstract available.
Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis.
Steinfeld J, Bradford ES, Brown J, Mallett S, Yancey SW, Akuthota P, Cid MC, Gleich GJ, Jayne D, Khoury P, Langford CA, Merkel PA, Moosig F, Specks U, Weller PF, Wechsler ME. Steinfeld J, et al. Among authors: akuthota p. J Allergy Clin Immunol. 2019 Jun;143(6):2170-2177. doi: 10.1016/j.jaci.2018.11.041. Epub 2018 Dec 19. J Allergy Clin Immunol. 2019. PMID: 30578883 Free PMC article. Clinical Trial.
Unmet Needs in Severe Asthma Subtyping and Precision Medicine Trials. Bridging Clinical and Patient Perspectives.
Siddiqui S, Denlinger LC, Fowler SJ, Akuthota P, Shaw DE, Heaney LG, Brown L, Castro M, Winders TA, Kraft M, Wagers S, Peters MC, Pavord ID, Walker S, Jarjour NN. Siddiqui S, et al. Among authors: akuthota p. Am J Respir Crit Care Med. 2019 Apr 1;199(7):823-829. doi: 10.1164/rccm.201809-1817PP. Am J Respir Crit Care Med. 2019. PMID: 30726120 Free PMC article. No abstract available.
Human Eosinophils Express a Distinct Gene Expression Program in Response to IL-3 Compared with Common β-Chain Cytokines IL-5 and GM-CSF.
Nelson RK, Brickner H, Panwar B, Ramírez-Suástegui C, Herrera-de la Mata S, Liu N, Diaz D, Alexander LEC, Ay F, Vijayanand P, Seumois G, Akuthota P. Nelson RK, et al. Among authors: akuthota p. J Immunol. 2019 Jul 15;203(2):329-337. doi: 10.4049/jimmunol.1801668. Epub 2019 Jun 7. J Immunol. 2019. PMID: 31175163 Free PMC article.
Eosinophilic Asthma.
Nelson RK, Bush A, Stokes J, Nair P, Akuthota P. Nelson RK, et al. Among authors: akuthota p. J Allergy Clin Immunol Pract. 2020 Feb;8(2):465-473. doi: 10.1016/j.jaip.2019.11.024. Epub 2019 Nov 28. J Allergy Clin Immunol Pract. 2020. PMID: 31786254
The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.
Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, Billheimer D, Bleecker ER, Cardet JC, Castro M, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Holguin F, Jain S, Kenyon NJ, Krishnan JA, Kraft M, Kumar R, Liu MC, Ly NP, Moy JN, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Wechsler ME, Wenzel SE, White SR. Ivanova A, et al. Among authors: akuthota p. J Biopharm Stat. 2020 Nov 1;30(6):1026-1037. doi: 10.1080/10543406.2020.1821705. Epub 2020 Sep 17. J Biopharm Stat. 2020. PMID: 32941098 Free PMC article. Clinical Trial.
76 results