Nobles M - Search Results

1

The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate.

Sebastian S, Nobles M, Tsisanova E, Ludwig A, Munroe PB, Tinker A. Sebastian S, et al. Among authors: nobles m. Physiol Genomics. 2021 Apr 1;53(4):150-159. doi: 10.1152/physiolgenomics.00157.2020. Epub 2021 Mar 15. Physiol Genomics. 2021. PMID: 33719582

2

Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle.

Leaney JL, Benians A, Brown S, Nobles M, Kelly D, Tinker A. Leaney JL, et al. Among authors: nobles m. Am J Physiol Cell Physiol. 2004 Jul;287(1):C182-91. doi: 10.1152/ajpcell.00540.2003. Epub 2004 Mar 10. Am J Physiol Cell Physiol. 2004. PMID: 15013952 Free article.

3

Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics.

Benians A, Nobles M, Hosny S, Tinker A. Benians A, et al. Among authors: nobles m. J Biol Chem. 2005 Apr 8;280(14):13383-94. doi: 10.1074/jbc.M410163200. Epub 2005 Jan 27. J Biol Chem. 2005. PMID: 15677457 Free article.

4

Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells.

Nobles M, Benians A, Tinker A. Nobles M, et al. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18706-11. doi: 10.1073/pnas.0504778102. Epub 2005 Dec 13. Proc Natl Acad Sci U S A. 2005. PMID: 16352729 Free PMC article.

5

Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behavior.

Mashanov GI, Nobles M, Harmer SC, Molloy JE, Tinker A. Mashanov GI, et al. Among authors: nobles m. J Biol Chem. 2010 Feb 5;285(6):3664-3675. doi: 10.1074/jbc.M109.039974. Epub 2009 Nov 23. J Biol Chem. 2010. PMID: 19940153 Free PMC article.

6

HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.

Nobles M, Sebastian S, Tinker A. Nobles M, et al. Pflugers Arch. 2010 Jun;460(1):99-108. doi: 10.1007/s00424-010-0799-z. Epub 2010 Feb 26. Pflugers Arch. 2010. PMID: 20186548 Free PMC article.

7

Absence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia.

Zuberi Z, Nobles M, Sebastian S, Dyson A, Lim SY, Breckenridge R, Birnbaumer L, Tinker A. Zuberi Z, et al. Among authors: nobles m. Circ Arrhythm Electrophysiol. 2010 Aug;3(4):391-400. doi: 10.1161/CIRCEP.109.894329. Epub 2010 May 21. Circ Arrhythm Electrophysiol. 2010. PMID: 20495013 Free PMC article.

8

Do caveolae have a role in the fidelity and dynamics of receptor activation of G-protein-gated inwardly rectifying potassium channels?

Schwarzer S, Nobles M, Tinker A. Schwarzer S, et al. Among authors: nobles m. J Biol Chem. 2010 Sep 3;285(36):27817-26. doi: 10.1074/jbc.M110.103598. Epub 2010 Jun 18. J Biol Chem. 2010. PMID: 20562107 Free PMC article.

9

In situ maleimide bridging of disulfides and a new approach to protein PEGylation.

Schumacher FF, Nobles M, Ryan CP, Smith ME, Tinker A, Caddick S, Baker JR. Schumacher FF, et al. Among authors: nobles m. Bioconjug Chem. 2011 Feb 16;22(2):132-6. doi: 10.1021/bc1004685. Epub 2011 Jan 27. Bioconjug Chem. 2011. PMID: 21271715 Free PMC article.

10

Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study.

Gomes J, Finlay M, Ahmed AK, Ciaccio EJ, Asimaki A, Saffitz JE, Quarta G, Nobles M, Syrris P, Chaubey S, McKenna WJ, Tinker A, Lambiase PD. Gomes J, et al. Among authors: nobles m. Eur Heart J. 2012 Aug;33(15):1942-53. doi: 10.1093/eurheartj/ehr472. Epub 2012 Jan 11. Eur Heart J. 2012. PMID: 22240500 Free PMC article.

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