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Page 1
Acute effect of inhaled iloprost on exercise dynamic hyperinflation in COPD patients: A randomized crossover study.
Lammi MR, Ghonim MA, Johnson J, D'Aquin J, Zamjahn JB, Pellett A, Okpechi SC, Romaine C, Pyakurel K, Luu HH, Shellito JE, Boulares AH, deBoisblanc BP. Lammi MR, et al. Among authors: ghonim ma. Respir Med. 2021 Apr-May;180:106354. doi: 10.1016/j.rmed.2021.106354. Epub 2021 Mar 8. Respir Med. 2021. PMID: 33721696 Free PMC article. Clinical Trial.
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonuclease that translocates to the nucleus during apoptosis.
Errami Y, Naura AS, Kim H, Ju J, Suzuki Y, El-Bahrawy AH, Ghonim MA, Hemeida RA, Mansy MS, Zhang J, Xu M, Smulson ME, Brim H, Boulares AH. Errami Y, et al. Among authors: ghonim ma. J Biol Chem. 2013 Feb 1;288(5):3460-8. doi: 10.1074/jbc.M112.423061. Epub 2012 Dec 10. J Biol Chem. 2013. PMID: 23229555 Free PMC article.
DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4⁺ T-cell function without causing severe combined immunodeficiency.
Ghonim MA, Pyakurel K, Ju J, Rodriguez PC, Lammi MR, Davis C, Abughazleh MQ, Mansy MS, Naura AS, Boulares AH. Ghonim MA, et al. J Allergy Clin Immunol. 2015 Feb;135(2):425-40. doi: 10.1016/j.jaci.2014.09.005. Epub 2014 Oct 19. J Allergy Clin Immunol. 2015. PMID: 25441643 Free PMC article.
Treatment with intranasal iloprost reduces disease manifestations in a murine model of previously established COPD.
Lammi MR, Ghonim MA, Pyakurel K, Naura AS, Ibba SV, Davis CJ, Okpechi SC, Happel KI, deBoisblanc BP, Shellito J, Boulares AH. Lammi MR, et al. Among authors: ghonim ma. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L630-8. doi: 10.1152/ajplung.00297.2015. Epub 2016 Feb 5. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26851260 Free PMC article.
ApoE deficiency promotes colon inflammation and enhances inflammatory potential oxidized-LDL and TNF-α in colon epithelial cells.
El-Bahrawy A, Tarhuni A, Kim H, Subramaniam V, Benslimane I, Abd Elmageed ZY, Okpechi S, Ghonim M, Hemeida R, Abo-Yousef A, El-Sherbiny G, Abdel-Raheem I, Kim J, Naura AS, Boulares H. El-Bahrawy A, et al. Biosci Rep. 2016 Oct;36(5):e00388. doi: 10.1042/BSR20160195. Epub 2016 Aug 18. Biosci Rep. 2016. PMID: 27538678 Free PMC article.
Fuelling the mechanisms of asthma: Increased fatty acid oxidation in inflammatory immune cells may represent a novel therapeutic target.
Al-Khami AA, Ghonim MA, Del Valle L, Ibba SV, Zheng L, Pyakurel K, Okpechi SC, Garay J, Wyczechowska D, Sanchez-Pino MD, Rodriguez PC, Boulares AH, Ochoa AC. Al-Khami AA, et al. Among authors: ghonim ma. Clin Exp Allergy. 2017 Sep;47(9):1170-1184. doi: 10.1111/cea.12947. Epub 2017 Jul 5. Clin Exp Allergy. 2017. PMID: 28456994 Free PMC article.
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