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Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Shi Y, et al. Among authors: higuchi m. Acta Neuropathol. 2021 May;141(5):697-708. doi: 10.1007/s00401-021-02294-3. Epub 2021 Mar 16. Acta Neuropathol. 2021. PMID: 33723967 Free PMC article.
In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders.
Maeda J, Zhang MR, Okauchi T, Ji B, Ono M, Hattori S, Kumata K, Iwata N, Saido TC, Trojanowski JQ, Lee VM, Staufenbiel M, Tomiyama T, Mori H, Fukumura T, Suhara T, Higuchi M. Maeda J, et al. Among authors: higuchi m. J Neurosci. 2011 Mar 23;31(12):4720-30. doi: 10.1523/JNEUROSCI.3076-10.2011. J Neurosci. 2011. PMID: 21430171 Free PMC article.
Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls.
Maruyama M, Shimada H, Suhara T, Shinotoh H, Ji B, Maeda J, Zhang MR, Trojanowski JQ, Lee VM, Ono M, Masamoto K, Takano H, Sahara N, Iwata N, Okamura N, Furumoto S, Kudo Y, Chang Q, Saido TC, Takashima A, Lewis J, Jang MK, Aoki I, Ito H, Higuchi M. Maruyama M, et al. Among authors: higuchi m. Neuron. 2013 Sep 18;79(6):1094-108. doi: 10.1016/j.neuron.2013.07.037. Neuron. 2013. PMID: 24050400 Free PMC article.
PET Quantification of Tau Pathology in Human Brain with 11C-PBB3.
Kimura Y, Ichise M, Ito H, Shimada H, Ikoma Y, Seki C, Takano H, Kitamura S, Shinotoh H, Kawamura K, Zhang MR, Sahara N, Suhara T, Higuchi M. Kimura Y, et al. Among authors: higuchi m. J Nucl Med. 2015 Sep;56(9):1359-65. doi: 10.2967/jnumed.115.160127. Epub 2015 Jul 16. J Nucl Med. 2015. PMID: 26182966 Free article.
Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.
Imamura K, Sahara N, Kanaan NM, Tsukita K, Kondo T, Kutoku Y, Ohsawa Y, Sunada Y, Kawakami K, Hotta A, Yawata S, Watanabe D, Hasegawa M, Trojanowski JQ, Lee VM, Suhara T, Higuchi M, Inoue H. Imamura K, et al. Among authors: higuchi m. Sci Rep. 2016 Oct 10;6:34904. doi: 10.1038/srep34904. Sci Rep. 2016. PMID: 27721502 Free PMC article.
2,026 results