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Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Monti G, Kjolby M, Jensen AMG, Allen M, Reiche J, Møller PL, Comaposada-Baró R, Zolkowski BE, Vieira C, Jørgensen MM, Holm IE, Valdmanis PN, Wellner N, Vægter CB, Lincoln SJ, Nykjær A, Ertekin-Taner N, Young JE, Nyegaard M, Andersen OM. Monti G, et al. Among authors: andersen om. Acta Neuropathol Commun. 2021 Mar 16;9(1):43. doi: 10.1186/s40478-021-01140-7. Acta Neuropathol Commun. 2021. PMID: 33726851 Free PMC article.
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X, Bales KR, Cappai R, Masters CL, Gliemann J, Mufson EJ, Hyman BT, Paul SM, Nykjaer A, Willnow TE. Andersen OM, et al. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13461-6. doi: 10.1073/pnas.0503689102. Epub 2005 Sep 7. Proc Natl Acad Sci U S A. 2005. PMID: 16174740 Free PMC article.
APP involvement in retinogenesis of mice.
Dinet V, An N, Ciccotosto GD, Bruban J, Maoui A, Bellingham SA, Hill AF, Andersen OM, Nykjaer A, Jonet L, Cappai R, Mascarelli F. Dinet V, et al. Among authors: andersen om. Acta Neuropathol. 2011 Mar;121(3):351-63. doi: 10.1007/s00401-010-0762-2. Epub 2010 Oct 27. Acta Neuropathol. 2011. PMID: 20978902
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.
Fjorback AW, Seaman M, Gustafsen C, Mehmedbasic A, Gokool S, Wu C, Militz D, Schmidt V, Madsen P, Nyengaard JR, Willnow TE, Christensen EI, Mobley WB, Nykjær A, Andersen OM. Fjorback AW, et al. Among authors: andersen om. J Neurosci. 2012 Jan 25;32(4):1467-80. doi: 10.1523/JNEUROSCI.2272-11.2012. J Neurosci. 2012. PMID: 22279231 Free PMC article.
SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
Glerup S, Bolcho U, Mølgaard S, Bøggild S, Vaegter CB, Smith AH, Nieto-Gonzalez JL, Ovesen PL, Pedersen LF, Fjorback AN, Kjolby M, Login H, Holm MM, Andersen OM, Nyengaard JR, Willnow TE, Jensen K, Nykjaer A. Glerup S, et al. Among authors: andersen om. Mol Psychiatry. 2016 Dec;21(12):1740-1751. doi: 10.1038/mp.2016.108. Epub 2016 Jul 26. Mol Psychiatry. 2016. PMID: 27457814
An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor.
Blechingberg J, Poulsen ASA, Kjølby M, Monti G, Allen M, Ivarsen AK, Lincoln SJ, Thotakura G, Vægter CB, Ertekin-Taner N, Nykjær A, Andersen OM. Blechingberg J, et al. Among authors: andersen om. Neurobiol Aging. 2018 Nov;71:266.e11-266.e24. doi: 10.1016/j.neurobiolaging.2018.06.021. Epub 2018 Jun 28. Neurobiol Aging. 2018. PMID: 30078640 Free PMC article.
SORLA regulates endosomal trafficking and oncogenic fitness of HER2.
Pietilä M, Sahgal P, Peuhu E, Jäntti NZ, Paatero I, Närvä E, Al-Akhrass H, Lilja J, Georgiadou M, Andersen OM, Padzik A, Sihto H, Joensuu H, Blomqvist M, Saarinen I, Boström PJ, Taimen P, Ivaska J. Pietilä M, et al. Among authors: andersen om. Nat Commun. 2019 May 28;10(1):2340. doi: 10.1038/s41467-019-10275-0. Nat Commun. 2019. PMID: 31138794 Free PMC article.
96 results