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Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Monti G, Kjolby M, Jensen AMG, Allen M, Reiche J, Møller PL, Comaposada-Baró R, Zolkowski BE, Vieira C, Jørgensen MM, Holm IE, Valdmanis PN, Wellner N, Vægter CB, Lincoln SJ, Nykjær A, Ertekin-Taner N, Young JE, Nyegaard M, Andersen OM. Monti G, et al. Among authors: kjolby m. Acta Neuropathol Commun. 2021 Mar 16;9(1):43. doi: 10.1186/s40478-021-01140-7. Acta Neuropathol Commun. 2021. PMID: 33726851 Free PMC article.
Sortilins: new players in lipoprotein metabolism.
Willnow TE, Kjølby M, Nykjaer A. Willnow TE, et al. Among authors: kjolby m. Curr Opin Lipidol. 2011 Apr;22(2):79-85. doi: 10.1097/MOL.0b013e3283416f2b. Curr Opin Lipidol. 2011. PMID: 21124217 Review.
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM. Glerup S, et al. Among authors: kjolby m. Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17. Cell Rep. 2013. PMID: 23333276 Free article.
The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.
Gustafsen C, Kjolby M, Nyegaard M, Mattheisen M, Lundhede J, Buttenschøn H, Mors O, Bentzon JF, Madsen P, Nykjaer A, Glerup S. Gustafsen C, et al. Among authors: kjolby m. Cell Metab. 2014 Feb 4;19(2):310-8. doi: 10.1016/j.cmet.2013.12.006. Cell Metab. 2014. PMID: 24506872 Free article.
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A. Glerup S, et al. Among authors: kjolby m. Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022. Neuron. 2014. PMID: 24908487 Free article.
SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
Glerup S, Bolcho U, Mølgaard S, Bøggild S, Vaegter CB, Smith AH, Nieto-Gonzalez JL, Ovesen PL, Pedersen LF, Fjorback AN, Kjolby M, Login H, Holm MM, Andersen OM, Nyengaard JR, Willnow TE, Jensen K, Nykjaer A. Glerup S, et al. Among authors: kjolby m. Mol Psychiatry. 2016 Dec;21(12):1740-1751. doi: 10.1038/mp.2016.108. Epub 2016 Jul 26. Mol Psychiatry. 2016. PMID: 27457814
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
Pottier C, Zhou X, Perkerson RB 3rd, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sánchez-Valle R, Antonell A, Lladó A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D,… See abstract for full author list ➔ Pottier C, et al. Among authors: kjolby m. Lancet Neurol. 2018 Jun;17(6):548-558. doi: 10.1016/S1474-4422(18)30126-1. Epub 2018 Apr 30. Lancet Neurol. 2018. PMID: 29724592 Free PMC article.
An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor.
Blechingberg J, Poulsen ASA, Kjølby M, Monti G, Allen M, Ivarsen AK, Lincoln SJ, Thotakura G, Vægter CB, Ertekin-Taner N, Nykjær A, Andersen OM. Blechingberg J, et al. Among authors: kjolby m. Neurobiol Aging. 2018 Nov;71:266.e11-266.e24. doi: 10.1016/j.neurobiolaging.2018.06.021. Epub 2018 Jun 28. Neurobiol Aging. 2018. PMID: 30078640 Free PMC article.
59 results