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Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Monti G, Kjolby M, Jensen AMG, Allen M, Reiche J, Møller PL, Comaposada-Baró R, Zolkowski BE, Vieira C, Jørgensen MM, Holm IE, Valdmanis PN, Wellner N, Vægter CB, Lincoln SJ, Nykjær A, Ertekin-Taner N, Young JE, Nyegaard M, Andersen OM. Monti G, et al. Among authors: nyegaard m. Acta Neuropathol Commun. 2021 Mar 16;9(1):43. doi: 10.1186/s40478-021-01140-7. Acta Neuropathol Commun. 2021. PMID: 33726851 Free PMC article.
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, Koster G, Prabakaran T, Nilsson SK, Kjaergaard MM, Bakke O, Nykjær A, Olivecrona G, Petersen CM, Nielsen MS. Klinger SC, et al. Among authors: nyegaard m. J Cell Sci. 2011 Apr 1;124(Pt 7):1095-105. doi: 10.1242/jcs.072538. Epub 2011 Mar 8. J Cell Sci. 2011. PMID: 21385844 Free article.
The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.
Gustafsen C, Kjolby M, Nyegaard M, Mattheisen M, Lundhede J, Buttenschøn H, Mors O, Bentzon JF, Madsen P, Nykjaer A, Glerup S. Gustafsen C, et al. Among authors: nyegaard m. Cell Metab. 2014 Feb 4;19(2):310-8. doi: 10.1016/j.cmet.2013.12.006. Cell Metab. 2014. PMID: 24506872 Free article.
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.
Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR. Jønsson KL, et al. Among authors: nyegaard m. Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391. Nat Commun. 2017. PMID: 28186168 Free PMC article.
Genetic Risk of Coronary Artery Disease, Features of Atherosclerosis, and Coronary Plaque Burden.
Christiansen MK, Nissen L, Winther S, Møller PL, Frost L, Johansen JK, Jensen HK, Guðbjartsson D, Holm H, Stefánsson K, Bøtker HE, Bøttcher M, Nyegaard M. Christiansen MK, et al. Among authors: nyegaard m. J Am Heart Assoc. 2020 Feb 4;9(3):e014795. doi: 10.1161/JAHA.119.014795. Epub 2020 Jan 25. J Am Heart Assoc. 2020. PMID: 31983321 Free PMC article.
Familial analysis reveals rare risk variants for migraine in regulatory regions.
Techlo TR, Rasmussen AH, Møller PL, Bøttcher M, Winther S, Davidsson OB, Olofsson IA, Chalmer MA, Kogelman LJA, Nyegaard M, Olesen J, Hansen TF. Techlo TR, et al. Among authors: nyegaard m. Neurogenetics. 2020 Jul;21(3):149-157. doi: 10.1007/s10048-020-00606-5. Epub 2020 Feb 19. Neurogenetics. 2020. PMID: 32076896 Free PMC article.
Sortilin as a Biomarker for Cardiovascular Disease Revisited.
Møller PL, Rohde PD, Winther S, Breining P, Nissen L, Nykjaer A, Bøttcher M, Nyegaard M, Kjolby M. Møller PL, et al. Among authors: nyegaard m. Front Cardiovasc Med. 2021 Apr 16;8:652584. doi: 10.3389/fcvm.2021.652584. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 33937362 Free PMC article.
Multi-Trait Genomic Risk Stratification for Type 2 Diabetes.
Rohde PD, Nyegaard M, Kjolby M, Sørensen P. Rohde PD, et al. Among authors: nyegaard m. Front Med (Lausanne). 2021 Sep 8;8:711208. doi: 10.3389/fmed.2021.711208. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34568370 Free PMC article.
Polygenic Risk Score-Enhanced Risk Stratification of Coronary Artery Disease in Patients With Stable Chest Pain.
Christiansen MK, Winther S, Nissen L, Vilhjálmsson BJ, Frost L, Johansen JK, Møller PL, Schmidt SE, Westra J, Holm NR, Jensen HK, Christiansen EH, Guðbjartsson DF, Hólm H, Stefánsson K, Bøtker HE, Bøttcher M, Nyegaard M. Christiansen MK, et al. Among authors: nyegaard m. Circ Genom Precis Med. 2021 Jun;14(3):e003298. doi: 10.1161/CIRCGEN.120.003298. Epub 2021 May 25. Circ Genom Precis Med. 2021. PMID: 34032468 Clinical Trial.
202 results