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Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Monti G, Kjolby M, Jensen AMG, Allen M, Reiche J, Møller PL, Comaposada-Baró R, Zolkowski BE, Vieira C, Jørgensen MM, Holm IE, Valdmanis PN, Wellner N, Vægter CB, Lincoln SJ, Nykjær A, Ertekin-Taner N, Young JE, Nyegaard M, Andersen OM. Monti G, et al. Among authors: vaegter cb. Acta Neuropathol Commun. 2021 Mar 16;9(1):43. doi: 10.1186/s40478-021-01140-7. Acta Neuropathol Commun. 2021. PMID: 33726851 Free PMC article.
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM. Glerup S, et al. Among authors: vaegter cb. Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17. Cell Rep. 2013. PMID: 23333276 Free article.
Sortilins in neurotrophic factor signaling.
Glerup S, Nykjaer A, Vaegter CB. Glerup S, et al. Among authors: vaegter cb. Handb Exp Pharmacol. 2014;220:165-89. doi: 10.1007/978-3-642-45106-5_7. Handb Exp Pharmacol. 2014. PMID: 24668473 Review.
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A. Glerup S, et al. Among authors: vaegter cb. Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022. Neuron. 2014. PMID: 24908487 Free article.
SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
Glerup S, Bolcho U, Mølgaard S, Bøggild S, Vaegter CB, Smith AH, Nieto-Gonzalez JL, Ovesen PL, Pedersen LF, Fjorback AN, Kjolby M, Login H, Holm MM, Andersen OM, Nyengaard JR, Willnow TE, Jensen K, Nykjaer A. Glerup S, et al. Among authors: vaegter cb. Mol Psychiatry. 2016 Dec;21(12):1740-1751. doi: 10.1038/mp.2016.108. Epub 2016 Jul 26. Mol Psychiatry. 2016. PMID: 27457814
An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor.
Blechingberg J, Poulsen ASA, Kjølby M, Monti G, Allen M, Ivarsen AK, Lincoln SJ, Thotakura G, Vægter CB, Ertekin-Taner N, Nykjær A, Andersen OM. Blechingberg J, et al. Among authors: vaegter cb. Neurobiol Aging. 2018 Nov;71:266.e11-266.e24. doi: 10.1016/j.neurobiolaging.2018.06.021. Epub 2018 Jun 28. Neurobiol Aging. 2018. PMID: 30078640 Free PMC article.
Peripheral Nerve Regeneration Is Independent From Schwann Cell p75NTR Expression.
Gonçalves NP, Mohseni S, El Soury M, Ulrichsen M, Richner M, Xiao J, Wood RJ, Andersen OM, Coulson EJ, Raimondo S, Murray SS, Vægter CB. Gonçalves NP, et al. Among authors: vaegter cb. Front Cell Neurosci. 2019 May 29;13:235. doi: 10.3389/fncel.2019.00235. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31191256 Free PMC article.
50 results