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Variants associated with HHIP expression have sex-differential effects on lung function.
Fawcett KA, Obeidat M, Melbourne C, Shrine N, Guyatt AL, John C, Luan J, Richmond A, Moksnes MR, Granell R, Weiss S, Imboden M, May-Wilson S, Hysi P, Boutin TS, Portas L, Flexeder C, Harris SE, Wang CA, Lyytikäinen LP, Palviainen T, Foong RE, Keidel D, Minelli C, Langenberg C, Bossé Y, Van den Berge M, Sin DD, Hao K, Campbell A, Porteous D, Padmanabhan S, Smith BH, Evans DM, Ring S, Langhammer A, Hveem K, Willer C, Ewert R, Stubbe B, Pirastu N, Klaric L, Joshi PK, Patasova K, Massimo M, Polasek O, Starr JM, Karrasch S, Strauch K, Meitinger T, Rudan I, Rantanen T, Pietiläinen K, Kähönen M, Raitakari OT, Hall GL, Sly PD, Pennell CE, Kaprio J, Lehtimäki T, Vitart V, Deary IJ, Jarvis D, Wilson JF, Spector T, Probst-Hensch N, Wareham NJ, Völzke H, Henderson J, Strachan DP, Brumpton BM, Hayward C, Hall IP, Tobin MD, Wain LV. Fawcett KA, et al. Among authors: sin dd. Wellcome Open Res. 2021 May 24;5:111. doi: 10.12688/wellcomeopenres.15846.2. eCollection 2020. Wellcome Open Res. 2021. PMID: 33728380 Free PMC article.
Molecular signature of smoking in human lung tissues.
Bossé Y, Postma DS, Sin DD, Lamontagne M, Couture C, Gaudreault N, Joubert P, Wong V, Elliott M, van den Berge M, Brandsma CA, Tribouley C, Malkov V, Tsou JA, Opiteck GJ, Hogg JC, Sandford AJ, Timens W, Paré PD, Laviolette M. Bossé Y, et al. Among authors: sin dd. Cancer Res. 2012 Aug 1;72(15):3753-63. doi: 10.1158/0008-5472.CAN-12-1160. Epub 2012 Jun 1. Cancer Res. 2012. PMID: 22659451 Free article.
Lung expression quantitative trait loci data set identifies important functional polymorphisms in the asthma-associated IL1RL1 region.
Akhabir L, Bérubé JC, Bossé Y, Laviolette M, Hao K, Nickle DC, Timens W, Sin DD, Paré PD, Postma DS, Sandford AJ. Akhabir L, et al. Among authors: sin dd. J Allergy Clin Immunol. 2014 Sep;134(3):729-31. doi: 10.1016/j.jaci.2014.02.039. Epub 2014 Apr 18. J Allergy Clin Immunol. 2014. PMID: 24746754 No abstract available.
Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.
Wain LV, Sayers I, Soler Artigas M, Portelli MA, Zeggini E, Obeidat M, Sin DD, Bossé Y, Nickle D, Brandsma CA, Malarstig A, Vangjeli C, Jelinsky SA, John S, Kilty I, McKeever T, Shrine NR, Cook JP, Patel S, Spector TD, Hollox EJ, Hall IP, Tobin MD. Wain LV, et al. Among authors: sin dd. PLoS Genet. 2014 May 1;10(5):e1004314. doi: 10.1371/journal.pgen.1004314. eCollection 2014 May. PLoS Genet. 2014. PMID: 24786987 Free PMC article.
Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.
Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, Lenburg ME, Spira A, Paré PD, Nickle D, Sin DD, Postma DS. Lamontagne M, et al. Among authors: sin dd. Thorax. 2014 Nov;69(11):997-1004. doi: 10.1136/thoraxjnl-2014-205630. Epub 2014 Sep 2. Thorax. 2014. PMID: 25182044
Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses.
Dijkstra AE, Postma DS, van Ginneken B, Wielpütz MO, Schmidt M, Becker N, Owsijewitsch M, Kauczor HU, de Koning HJ, Lammers JW, Oudkerk M, Brandsma CA, Bossé Y, Nickle DC, Sin DD, Hiemstra PS, Wijmenga C, Smolonska J, Zanen P, Vonk JM, van den Berge M, Boezen HM, Groen HJ. Dijkstra AE, et al. Among authors: sin dd. Am J Respir Crit Care Med. 2015 Mar 1;191(5):547-56. doi: 10.1164/rccm.201405-0840OC. Am J Respir Crit Care Med. 2015. PMID: 25517131
625 results