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Statistical integration of two omics datasets using GO2PLS.
Gu Z, El Bouhaddani S, Pei J, Houwing-Duistermaat J, Uh HW. Gu Z, et al. Among authors: pei j. BMC Bioinformatics. 2021 Mar 18;22(1):131. doi: 10.1186/s12859-021-03958-3. BMC Bioinformatics. 2021. PMID: 33736604 Free PMC article.
Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations.
Pei J, Schuldt M, Nagyova E, Gu Z, El Bouhaddani S, Yiangou L, Jansen M, Calis JJA, Dorsch LM, Blok CS, van den Dungen NAM, Lansu N, Boukens BJ, Efimov IR, Michels M, Verhaar MC, de Weger R, Vink A, van Steenbeek FG, Baas AF, Davis RP, Uh HW, Kuster DWD, Cheng C, Mokry M, van der Velden J, Asselbergs FW, Harakalova M. Pei J, et al. Clin Epigenetics. 2021 Mar 23;13(1):61. doi: 10.1186/s13148-021-01043-3. Clin Epigenetics. 2021. PMID: 33757590 Free PMC article.
Strength of patient cohorts and biobanks for cardiomyopathy research.
de Boer RA, Nijenkamp LLAM, Silljé HHW, Eijgenraam TR, Parbhudayal R, van Driel B, Huurman R, Michels M, Pei J, Harakalova M, van Lint FHM, Jansen M, Baas AF, Asselbergs FW, van Tintelen JP, Brundel BJJM, Dorsch LM, Schuldt M, Kuster DWD, van der Velden J; DOSIS consortium. de Boer RA, et al. Among authors: pei j. Neth Heart J. 2020 Aug;28(Suppl 1):50-56. doi: 10.1007/s12471-020-01456-4. Neth Heart J. 2020. PMID: 32780332 Free PMC article. Review.
H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts.
Pei J, Harakalova M, Treibel TA, Lumbers RT, Boukens BJ, Efimov IR, van Dinter JT, González A, López B, El Azzouzi H, van den Dungen N, van Dijk CGM, Krebber MM, den Ruijter HM, Pasterkamp G, Duncker DJ, Nieuwenhuis EES, de Weger R, Huibers MM, Vink A, Moore JH, Moon JC, Verhaar MC, Kararigas G, Mokry M, Asselbergs FW, Cheng C. Pei J, et al. Clin Epigenetics. 2020 Jul 14;12(1):106. doi: 10.1186/s13148-020-00895-5. Clin Epigenetics. 2020. PMID: 32664951 Free PMC article.
Integrative Functional Annotation of 52 Genetic Loci Influencing Myocardial Mass Identifies Candidate Regulatory Variants and Target Genes.
Hemerich D, Pei J, Harakalova M, van Setten J, Boymans S, Boukens BJ, Efimov IR, Michels M, van der Velden J, Vink A, Cheng C, van der Harst P, Moore JH, Mokry M, Tragante V, Asselbergs FW. Hemerich D, et al. Among authors: pei j. Circ Genom Precis Med. 2019 Feb;12(2):e002328. doi: 10.1161/CIRCGEN.118.002328. Circ Genom Precis Med. 2019. PMID: 30681347 Free PMC article.
A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix.
van Dijk CGM, Brandt MM, Poulis N, Anten J, van der Moolen M, Kramer L, Homburg EFGA, Louzao-Martinez L, Pei J, Krebber MM, van Balkom BWM, de Graaf P, Duncker DJ, Verhaar MC, Luttge R, Cheng C. van Dijk CGM, et al. Among authors: pei j. Lab Chip. 2020 May 19;20(10):1827-1844. doi: 10.1039/d0lc00059k. Lab Chip. 2020. PMID: 32330215
Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.
Schuldt M, Pei J, Harakalova M, Dorsch LM, Schlossarek S, Mokry M, Knol JC, Pham TV, Schelfhorst T, Piersma SR, Dos Remedios C, Dalinghaus M, Michels M, Asselbergs FW, Moutin MJ, Carrier L, Jimenez CR, van der Velden J, Kuster DWD. Schuldt M, et al. Among authors: pei j. Circ Heart Fail. 2021 Jan;14(1):e007022. doi: 10.1161/CIRCHEARTFAILURE.120.007022. Epub 2021 Jan 12. Circ Heart Fail. 2021. PMID: 33430602 Free PMC article.
2,534 results