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Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.
Luciano M, Hagenaars SP, Davies G, Hill WD, Clarke TK, Shirali M, Harris SE, Marioni RE, Liewald DC, Fawns-Ritchie C, Adams MJ, Howard DM, Lewis CM, Gale CR, McIntosh AM, Deary IJ. Luciano M, et al. Among authors: hagenaars sp. Nat Genet. 2018 Jan;50(1):6-11. doi: 10.1038/s41588-017-0013-8. Epub 2017 Dec 18. Nat Genet. 2018. PMID: 29255261 Free PMC article.
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J; 23andMe Research Team; Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Nat Commun. 2018 Apr 16;9(1):1470. doi: 10.1038/s41467-018-03819-3. Nat Commun. 2018. PMID: 29662059 Free PMC article.
Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J, Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Nat Commun. 2018 Aug 30;9(1):3578. doi: 10.1038/s41467-018-05310-5. Nat Commun. 2018. PMID: 30166530 Free PMC article. No abstract available.
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Nat Neurosci. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718901 Free PMC article.
Cannabis use, depression and self-harm: phenotypic and genetic relationships.
Hodgson K, Coleman JRI, Hagenaars SP, Purves KL, Glanville K, Choi SW, O'Reilly P, Breen G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Lewis CM. Hodgson K, et al. Among authors: hagenaars sp. Addiction. 2020 Mar;115(3):482-492. doi: 10.1111/add.14845. Epub 2019 Dec 12. Addiction. 2020. PMID: 31833150
Genetic stratification of depression in UK Biobank.
Howard DM, Folkersen L, Coleman JRI, Adams MJ, Glanville K, Werge T, Hagenaars SP, Han B, Porteous D, Campbell A, Clarke TK, Breen G, Sullivan PF, Wray NR, Lewis CM, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Transl Psychiatry. 2020 May 24;10(1):163. doi: 10.1038/s41398-020-0848-0. Transl Psychiatry. 2020. PMID: 32448866 Free PMC article.
80 results