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An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis.
Vassos E, Di Forti M, Coleman J, Iyegbe C, Prata D, Euesden J, O'Reilly P, Curtis C, Kolliakou A, Patel H, Newhouse S, Traylor M, Ajnakina O, Mondelli V, Marques TR, Gardner-Sood P, Aitchison KJ, Powell J, Atakan Z, Greenwood KE, Smith S, Ismail K, Pariante C, Gaughran F, Dazzan P, Markus HS, David AS, Lewis CM, Murray RM, Breen G. Vassos E, et al. Among authors: lewis cm. Biol Psychiatry. 2017 Mar 15;81(6):470-477. doi: 10.1016/j.biopsych.2016.06.028. Epub 2016 Aug 6. Biol Psychiatry. 2017. PMID: 27765268 Free article.
Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.
Milaneschi Y, Lamers F, Peyrot WJ, Baune BT, Breen G, Dehghan A, Forstner AJ, Grabe HJ, Homuth G, Kan C, Lewis C, Mullins N, Nauck M, Pistis G, Preisig M, Rivera M, Rietschel M, Streit F, Strohmaier J, Teumer A, Van der Auwera S, Wray NR, Boomsma DI, Penninx BWJH; CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Milaneschi Y, et al. JAMA Psychiatry. 2017 Dec 1;74(12):1214-1225. doi: 10.1001/jamapsychiatry.2017.3016. JAMA Psychiatry. 2017. PMID: 29049554 Free PMC article.
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes.
Rietschel L, Streit F, Zhu G, McAloney K, Frank J, Couvy-Duchesne B, Witt SH, Binz TM; CORtisolNETwork (CORNET) Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC); McGrath J, Hickie IB, Hansell NK, Wright MJ, Gillespie NA, Forstner AJ, Schulze TG, Wüst S, Nöthen MM, Baumgartner MR, Walker BR, Crawford AA, Colodro-Conde L, Medland SE, Martin NG, Rietschel M. Rietschel L, et al. Sci Rep. 2017 Nov 10;7(1):15351. doi: 10.1038/s41598-017-11852-3. Sci Rep. 2017. PMID: 29127340 Free PMC article. Clinical Trial.
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.
Luciano M, Hagenaars SP, Davies G, Hill WD, Clarke TK, Shirali M, Harris SE, Marioni RE, Liewald DC, Fawns-Ritchie C, Adams MJ, Howard DM, Lewis CM, Gale CR, McIntosh AM, Deary IJ. Luciano M, et al. Among authors: lewis cm. Nat Genet. 2018 Jan;50(1):6-11. doi: 10.1038/s41588-017-0013-8. Epub 2017 Dec 18. Nat Genet. 2018. PMID: 29255261 Free PMC article.
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J; 23andMe Research Team; Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Howard DM, et al. Among authors: lewis cm. Nat Commun. 2018 Apr 16;9(1):1470. doi: 10.1038/s41467-018-03819-3. Nat Commun. 2018. PMID: 29662059 Free PMC article.
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu, et al. Cell. 2018 Jun 14;173(7):1705-1715.e16. doi: 10.1016/j.cell.2018.05.046. Cell. 2018. PMID: 29906448 Free PMC article.
Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J, Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Howard DM, et al. Among authors: lewis cm. Nat Commun. 2018 Aug 30;9(1):3578. doi: 10.1038/s41467-018-05310-5. Nat Commun. 2018. PMID: 30166530 Free PMC article. No abstract available.
Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank.
Barbu MC, Zeng Y, Shen X, Cox SR, Clarke TK, Gibson J, Adams MJ, Johnstone M, Haley CS, Lawrie SM, Deary IJ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team; McIntosh AM, Whalley HC. Barbu MC, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Jan;4(1):91-100. doi: 10.1016/j.bpsc.2018.07.006. Epub 2018 Jul 31. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019. PMID: 30197049 Free PMC article.
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium; Curtis C, Newhouse SJ, Patel H, Hall LS, O Reilly PF, Belangero SI, Bressan RA, Breen G. de Jong S, et al. Commun Biol. 2018 Oct 8;1:163. doi: 10.1038/s42003-018-0155-y. eCollection 2018. Commun Biol. 2018. PMID: 30320231 Free PMC article.
783 results