Koch WJ - Search Results

1

A peptide of the N terminus of GRK5 attenuates pressure-overload hypertrophy and heart failure.

Coleman RC, Eguchi A, Lieu M, Roy R, Barr EW, Ibetti J, Lucchese AM, Peluzzo AM, Gresham K, Chuprun JK, Koch WJ. Coleman RC, et al. Among authors: koch wj. Sci Signal. 2021 Mar 30;14(676):eabb5968. doi: 10.1126/scisignal.abb5968. Sci Signal. 2021. PMID: 33785612 Free PMC article.

2

Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart.

Gao E, Boucher M, Chuprun JK, Zhou RH, Eckhart AD, Koch WJ. Gao E, et al. Among authors: koch wj. Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H60-8. doi: 10.1152/ajpheart.00227.2007. Epub 2007 Mar 23. Am J Physiol Heart Circ Physiol. 2007. PMID: 17384131 Free article.

3

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue.

Pleger ST, Most P, Boucher M, Soltys S, Chuprun JK, Pleger W, Gao E, Dasgupta A, Rengo G, Remppis A, Katus HA, Eckhart AD, Rabinowitz JE, Koch WJ. Pleger ST, et al. Among authors: koch wj. Circulation. 2007 May 15;115(19):2506-15. doi: 10.1161/CIRCULATIONAHA.106.671701. Epub 2007 Apr 30. Circulation. 2007. PMID: 17470693

4

Endothelial S100A1 modulates vascular function via nitric oxide.

Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P. Pleger ST, et al. Among authors: koch wj. Circ Res. 2008 Apr 11;102(7):786-94. doi: 10.1161/CIRCRESAHA.108.172031. Epub 2008 Feb 21. Circ Res. 2008. PMID: 18292599

5

Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.

DeGeorge BR Jr, Gao E, Boucher M, Vinge LE, Martini JS, Raake PW, Chuprun JK, Harris DM, Kim GW, Soltys S, Eckhart AD, Koch WJ. DeGeorge BR Jr, et al. Among authors: koch wj. Circulation. 2008 Mar 18;117(11):1378-87. doi: 10.1161/CIRCULATIONAHA.107.752618. Epub 2008 Mar 3. Circulation. 2008. PMID: 18316484

6

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.

Raake PW, Vinge LE, Gao E, Boucher M, Rengo G, Chen X, DeGeorge BR Jr, Matkovich S, Houser SR, Most P, Eckhart AD, Dorn GW 2nd, Koch WJ. Raake PW, et al. Among authors: koch wj. Circ Res. 2008 Aug 15;103(4):413-22. doi: 10.1161/CIRCRESAHA.107.168336. Epub 2008 Jul 17. Circ Res. 2008. PMID: 18635825 Free PMC article.

7

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes.

Martini JS, Raake P, Vinge LE, DeGeorge BR Jr, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ. Martini JS, et al. Among authors: koch wj. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12457-62. doi: 10.1073/pnas.0803153105. Epub 2008 Aug 18. Proc Natl Acad Sci U S A. 2008. PMID: 18711143 Free PMC article.

8

Dynamic changes in lymphocyte GRK2 levels in cardiac transplant patients: a biomarker for left ventricular function.

Bonita RE, Raake PW, Otis NJ, Chuprun JK, Spivack T, Dasgupta A, Whellan DJ, Mather PJ, Koch WJ. Bonita RE, et al. Among authors: koch wj. Clin Transl Sci. 2010 Feb;3(1):14-8. doi: 10.1111/j.1752-8062.2010.00176.x. Clin Transl Sci. 2010. PMID: 20443948 Free PMC article.

9

GRK2 as a novel gene therapy target in heart failure.

Rengo G, Lymperopoulos A, Leosco D, Koch WJ. Rengo G, et al. Among authors: koch wj. J Mol Cell Cardiol. 2011 May;50(5):785-92. doi: 10.1016/j.yjmcc.2010.08.014. Epub 2010 Aug 25. J Mol Cell Cardiol. 2011. PMID: 20800067 Free PMC article. Review.

10

Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.

Brinks H, Boucher M, Gao E, Chuprun JK, Pesant S, Raake PW, Huang ZM, Wang X, Qiu G, Gumpert A, Harris DM, Eckhart AD, Most P, Koch WJ. Brinks H, et al. Among authors: koch wj. Circ Res. 2010 Oct 29;107(9):1140-9. doi: 10.1161/CIRCRESAHA.110.221010. Epub 2010 Sep 2. Circ Res. 2010. PMID: 20814022 Free PMC article.

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