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Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.
Roux B, Vaganay C, Vargas JD, Alexe G, Benaksas C, Pardieu B, Fenouille N, Ellegast JM, Malolepsza E, Ling F, Sodaro G, Ross L, Pikman Y, Conway AS, Tang Y, Wu T, Anderson DJ, Le Moigne R, Zhou HJ, Luciano F, Hartigan CR, Galinsky I, DeAngelo DJ, Stone RM, Auberger P, Schenone M, Carr SA, Guirouilh-Barbat J, Lopez B, Khaled M, Lage K, Hermine O, Hemann MT, Puissant A, Stegmaier K, Benajiba L. Roux B, et al. Sci Transl Med. 2021 Mar 31;13(587):eabg1168. doi: 10.1126/scitranslmed.abg1168. Sci Transl Med. 2021. PMID: 33790022 Free PMC article.
RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair.
Mamouni K, Cristini A, Guirouilh-Barbat J, Monferran S, Lemarié A, Faye JC, Lopez BS, Favre G, Sordet O. Mamouni K, et al. Mol Cell Biol. 2014 Aug;34(16):3144-55. doi: 10.1128/MCB.01525-13. Epub 2014 Jun 9. Mol Cell Biol. 2014. PMID: 24912678 Free PMC article.
Is homologous recombination really an error-free process?
Guirouilh-Barbat J, Lambert S, Bertrand P, Lopez BS. Guirouilh-Barbat J, et al. Front Genet. 2014 Jun 11;5:175. doi: 10.3389/fgene.2014.00175. eCollection 2014. Front Genet. 2014. PMID: 24966870 Free PMC article. Review.
Control of alternative end joining by the chromatin remodeler p400 ATPase.
Taty-Taty GC, Chailleux C, Quaranta M, So A, Guirouilh-Barbat J, Lopez BS, Bertrand P, Trouche D, Canitrot Y. Taty-Taty GC, et al. Nucleic Acids Res. 2016 Feb 29;44(4):1657-68. doi: 10.1093/nar/gkv1202. Epub 2015 Nov 17. Nucleic Acids Res. 2016. PMID: 26578561 Free PMC article.
41 results