Wang M - Search Results

1

Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity.

Yu W, Liu J, Clausen D, Yu Y, Duffy JL, Wang M, Xu S, Deng L, Suzuki T, Chung CC, Myers RW, Klein DJ, Fells JI, Holloway MK, Wu J, Wu G, Howell BJ, Barnard RJO, Kozlowski J. Yu W, et al. Among authors: wang m. J Med Chem. 2021 Apr 22;64(8):4709-4729. doi: 10.1021/acs.jmedchem.0c02150. Epub 2021 Apr 2. J Med Chem. 2021. PMID: 33797924

2

Synthesis of HDAC Inhibitor Libraries via Microscale Workflow.

Dykstra KD, Streckfuss E, Liu M, Liu J, Yu Y, Wang M, Kozlowski JA, Myers RW, Buevich AV, Maletic MM, Vachal P, Krska SW. Dykstra KD, et al. Among authors: wang m. ACS Med Chem Lett. 2021 Feb 8;12(3):337-342. doi: 10.1021/acsmedchemlett.0c00596. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33738059 Free PMC article.

3

Fragment-based lead discovery of a novel class of small molecule antagonists of neuropeptide B/W receptor subtype 1 (GPR7).

Moningka R, Romero FA, Hastings NB, Guo Z, Wang M, Di Salvo J, Li Y, Trusca D, Deng Q, Tong V, Terebetski JL, Ball RG, Ujjainwalla F. Moningka R, et al. Among authors: wang m. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127510. doi: 10.1016/j.bmcl.2020.127510. Epub 2020 Sep 6. Bioorg Med Chem Lett. 2020. PMID: 32898693

4

The discovery of potent antagonists of NPBWR1 (GPR7).

Anthony Romero F, Hastings NB, Moningka R, Guo Z, Wang M, Di Salvo J, Lei Y, Trusca D, Deng Q, Tong V, Terebetski JL, Ball RG, Ujjainwalla F. Anthony Romero F, et al. Among authors: wang m. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1014-8. doi: 10.1016/j.bmcl.2011.11.126. Epub 2011 Dec 8. Bioorg Med Chem Lett. 2012. PMID: 22197390

5

Substituted indanylacetic acids as PPAR-alpha-gamma activators.

Lowe DB, Bifulco N, Bullock WH, Claus T, Coish P, Dai M, Dela Cruz FE, Dickson D, Fan D, Hoover-Litty H, Li T, Ma X, Mannelly G, Monahan MK, Muegge I, O'Connor S, Rodriguez M, Shelekhin T, Stolle A, Sweet L, Wang M, Wang Y, Zhang C, Zhang HJ, Zhang M, Zhao K, Zhao Q, Zhu J, Zhu L, Tsutsumi M. Lowe DB, et al. Among authors: wang y, wang m. Bioorg Med Chem Lett. 2006 Jan 15;16(2):297-301. doi: 10.1016/j.bmcl.2005.10.008. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275080

6

4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17beta-hydroxysteroid dehydrogenase. Part 2. SAR.

Gunn D, Akuche C, Baryza J, Blue ML, Brennan C, Campbell AM, Choi S, Cook J, Conrad P, Dixon B, Dumas J, Ehrlich P, Gane T, Joe T, Johnson J, Jordan J, Kramss R, Liu P, Levy J, Lowe D, McAlexander I, Natero R, Redman AM, Scott W, Seng T, Sibley R, Wang M, Wang Y, Wood J, Zhang Z. Gunn D, et al. Among authors: wang y, wang m. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3053-7. doi: 10.1016/j.bmcl.2005.04.025. Bioorg Med Chem Lett. 2005. PMID: 15890515

7

Design, synthesis, fungicidal activity and molecular docking studies of novel 2-((2-hydroxyphenyl)methylamino)acetamide derivatives.

Tang Z, Li X, Yao Y, Qi Y, Wang M, Dai N, Wen Y, Wan Y, Peng L. Tang Z, et al. Among authors: wang m. Bioorg Med Chem. 2019 Jun 15;27(12):2572-2578. doi: 10.1016/j.bmc.2019.03.040. Epub 2019 Mar 20. Bioorg Med Chem. 2019. PMID: 30910475

8

Discovery of Pyrrole-imidazole Polyamides as PD-L1 Expression Inhibitors and Their Anticancer Activity via Immune and Nonimmune Pathways.

Wang M, Ma X, Zhou K, Mao H, Liu J, Xiong X, Zhao X, Narva S, Tanaka Y, Wu Y, Guo C, Sugiyama H, Zhang W. Wang M, et al. J Med Chem. 2021 May 13;64(9):6021-6036. doi: 10.1021/acs.jmedchem.1c00120. Epub 2021 May 5. J Med Chem. 2021. PMID: 33949196

9

4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17beta-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate.

Wood J, Bagi CM, Akuche C, Bacchiocchi A, Baryza J, Blue ML, Brennan C, Campbell AM, Choi S, Cook JH, Conrad P, Dixon BR, Ehrlich PP, Gane T, Gunn D, Joe T, Johnson JS, Jordan J, Kramss R, Liu P, Levy J, Lowe DB, McAlexander I, Natero R, Redman AM, Scott WJ, Town C, Wang M, Wang Y, Zhang Z. Wood J, et al. Among authors: wang y, wang m. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4965-8. doi: 10.1016/j.bmcl.2006.06.041. Epub 2006 Jun 27. Bioorg Med Chem Lett. 2006. PMID: 16806919

10

In vitro SAR of (5-(2H)-isoxazolonyl) ureas, potent inhibitors of hormone-sensitive lipase.

Lowe DB, Magnuson S, Qi N, Campbell AM, Cook J, Hong Z, Wang M, Rodriguez M, Achebe F, Kluender H, Wong WC, Bullock WH, Salhanick AI, Witman-Jones T, Bowling ME, Keiper C, Clairmont KB. Lowe DB, et al. Among authors: wang m. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3155-9. doi: 10.1016/j.bmcl.2004.04.015. Bioorg Med Chem Lett. 2004. PMID: 15149665

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