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A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics.
Hava DL, Tan L, Johnson P, Curran AK, Perry J, Kramer S, Kane K, Bedwell P, Layton G, Swann C, Henderson D, Khan N, Connor L, McKenzie L, Singh D, Roach J. Hava DL, et al. Br J Clin Pharmacol. 2020 Apr;86(4):723-733. doi: 10.1111/bcp.14166. Epub 2020 Jan 16. Br J Clin Pharmacol. 2020. PMID: 31696544 Free PMC article. Clinical Trial.
A New Natural Defense Against Airborne Pathogens.
Edwards D, Hickey A, Batycky R, Griel L, Lipp M, Dehaan W, Clarke R, Hava D, Perry J, Laurenzi B, Curran AK, Beddingfield BJ, Roy CJ, Devlin T, Langer R. Edwards D, et al. QRB Discov. 2020 Jul 7;1:e5. doi: 10.1017/qrd.2020.9. eCollection 2020. QRB Discov. 2020. PMID: 34192261 Free PMC article.
An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria.
Lubkowicz D, Horvath NG, James MJ, Cantarella P, Renaud L, Bergeron CG, Shmueli RB, Anderson C, Gao JR, Kurtz CB, Perreault M, Charbonneau MR, Isabella VM, Hava DL. Lubkowicz D, et al. Among authors: hava dl. Mol Syst Biol. 2022 Mar;18(3):e10539. doi: 10.15252/msb.202110539. Mol Syst Biol. 2022. PMID: 35253995 Free PMC article.
Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler.
Perry J, Trautman B, Takher-Smith J, Kramer S, Kane K, Silverman M, Tan L, Haughie S, Richter W, Kirkov V, Arsova S, Ward J, Hava DL. Perry J, et al. Among authors: hava dl. Br J Clin Pharmacol. 2019 Mar;85(3):580-589. doi: 10.1111/bcp.13831. Epub 2019 Jan 15. Br J Clin Pharmacol. 2019. PMID: 30521129 Free PMC article. Clinical Trial.
31 results