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A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.
Horn IP, Marks DL, Koenig AN, Hogenson TL, Almada LL, Goldstein LE, Romecin Duran PA, Vera R, Vrabel AM, Cui G, Rabe KG, Bamlet WR, Mer G, Sicotte H, Zhang C, Li H, Petersen GM, Fernandez-Zapico ME. Horn IP, et al. Among authors: petersen gm. J Biol Chem. 2021 Jan-Jun;296:100634. doi: 10.1016/j.jbc.2021.100634. Epub 2021 Apr 3. J Biol Chem. 2021. PMID: 33823155 Free PMC article.
The APC E1317Q variant in adenomatous polyps and colorectal cancers.
Hahnloser D, Petersen GM, Rabe K, Snow K, Lindor NM, Boardman L, Koch B, Doescher D, Wang L, Steenblock K, Thibodeau SN. Hahnloser D, et al. Among authors: petersen gm. Cancer Epidemiol Biomarkers Prev. 2003 Oct;12(10):1023-8. Cancer Epidemiol Biomarkers Prev. 2003. PMID: 14578138
Pancreatic cancer genetic epidemiology consortium.
Petersen GM, de Andrade M, Goggins M, Hruban RH, Bondy M, Korczak JF, Gallinger S, Lynch HT, Syngal S, Rabe KG, Seminara D, Klein AP. Petersen GM, et al. Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):704-10. doi: 10.1158/1055-9965.EPI-05-0734. Cancer Epidemiol Biomarkers Prev. 2006. PMID: 16614112
The prevalence of BRCA2 mutations in familial pancreatic cancer.
Couch FJ, Johnson MR, Rabe KG, Brune K, de Andrade M, Goggins M, Rothenmund H, Gallinger S, Klein A, Petersen GM, Hruban RH. Couch FJ, et al. Among authors: petersen gm. Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):342-6. doi: 10.1158/1055-9965.EPI-06-0783. Cancer Epidemiol Biomarkers Prev. 2007. PMID: 17301269
424 results