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Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2000017118. doi: 10.1073/pnas.2000017118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33846240
Free PMC article.
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In vivo effects of μ-opioid receptor agonist/δ-opioid receptor antagonist peptidomimetics following acute and repeated administration.
Anand JP, Kochan KE, Nastase AF, Montgomery D, Griggs NW, Traynor JR, Mosberg HI, Jutkiewicz EM.
Anand JP, et al. Among authors: kochan ke.
Br J Pharmacol. 2018 Jun;175(11):2013-2027. doi: 10.1111/bph.14148. Epub 2018 Apr 24.
Br J Pharmacol. 2018.
PMID: 29352503
Free PMC article.
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Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management.
Senese NB, Kandasamy R, Kochan KE, Traynor JR.
Senese NB, et al. Among authors: kochan ke.
Front Mol Neurosci. 2020 Jan 24;13:5. doi: 10.3389/fnmol.2020.00005. eCollection 2020.
Front Mol Neurosci. 2020.
PMID: 32038168
Free PMC article.
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