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Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.
Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li MH, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR. Kandasamy R, et al. Among authors: roques bp. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2000017118. doi: 10.1073/pnas.2000017118. Proc Natl Acad Sci U S A. 2021. PMID: 33846240 Free PMC article.
Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor.
Matthes HW, Smadja C, Valverde O, Vonesch JL, Foutz AS, Boudinot E, Denavit-Saubié M, Severini C, Negri L, Roques BP, Maldonado R, Kieffer BL. Matthes HW, et al. Among authors: roques bp. J Neurosci. 1998 Sep 15;18(18):7285-95. doi: 10.1523/JNEUROSCI.18-18-07285.1998. J Neurosci. 1998. PMID: 9736649 Free PMC article.
Highly selective photoaffinity labeling of mu and delta opioid receptors.
Garbay-Jaureguiberry C, Robichon A, Daugé V, Rossignol P, Roques BP. Garbay-Jaureguiberry C, et al. Among authors: roques bp. Proc Natl Acad Sci U S A. 1984 Dec;81(24):7718-22. doi: 10.1073/pnas.81.24.7718. Proc Natl Acad Sci U S A. 1984. PMID: 6096852 Free PMC article.
Aminopeptidase A inhibitors as potential central antihypertensive agents.
Reaux A, Fournie-Zaluski MC, David C, Zini S, Roques BP, Corvol P, Llorens-Cortes C. Reaux A, et al. Among authors: roques bp. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13415-20. doi: 10.1073/pnas.96.23.13415. Proc Natl Acad Sci U S A. 1999. PMID: 10557335 Free PMC article.
696 results