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Monocyte metabolic transcriptional programs associate with resistance to tuberculin skin test/interferon-γ release assay conversion.
Simmons JD, Van PT, Stein CM, Chihota V, Ntshiqa T, Maenetje P, Peterson GJ, Reynolds A, Benchek P, Velen K, Fielding KL, Grant AD, Graustein AD, Nguyen FK, Seshadri C, Gottardo R, Mayanja-Kizza H, Wallis RS, Churchyard G, Boom WH, Hawn TR. Simmons JD, et al. Among authors: graustein ad. J Clin Invest. 2021 Jul 15;131(14):e140073. doi: 10.1172/JCI140073. J Clin Invest. 2021. PMID: 34111032 Free PMC article. Clinical Trial.
REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk.
Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, Thuong NTT, Thwaites GE, Caws M, Thai PVK, Bang ND, Chau TTH, Khor CC, Li Z, Hibberd M, Chang X, Nguyen FK, Hernandez CA, Jones MA, Sassetti CM, Fitzgerald KA, Musvosvi M, Gela A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. Shah JA, et al. Among authors: graustein ad. J Immunol. 2022 Mar 15;208(6):1352-1361. doi: 10.4049/jimmunol.2100671. Epub 2022 Feb 25. J Immunol. 2022. PMID: 35217585 Free PMC article.
Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria.
Graustein AD, Misch EA, Musvosvi M, Shey M, Shah JA, Seshadri C, Ajuogu A, Bowman K, Mulenga H, Veldsman A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. Graustein AD, et al. PLoS One. 2018 Dec 14;13(12):e0208940. doi: 10.1371/journal.pone.0208940. eCollection 2018. PLoS One. 2018. PMID: 30550567 Free PMC article.
The SIGLEC14 null allele is associated with Mycobacterium tuberculosis- and BCG-induced clinical and immunologic outcomes.
Graustein AD, Horne DJ, Fong JJ, Schwarz F, Mefford HC, Peterson GJ, Wells RD, Musvosvi M, Shey M, Hanekom WA, Hatherill M, Scriba TJ, Thuong NTT, Mai NTH, Caws M, Bang ND, Dunstan SJ, Thwaites GE, Varki A, Angata T, Hawn TR. Graustein AD, et al. Tuberculosis (Edinb). 2017 May;104:38-45. doi: 10.1016/j.tube.2017.02.005. Epub 2017 Feb 21. Tuberculosis (Edinb). 2017. PMID: 28454648 Free PMC article.
TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam.
Graustein AD, Horne DJ, Arentz M, Bang ND, Chau TT, Thwaites GE, Caws M, Thuong NT, Dunstan SJ, Hawn TR. Graustein AD, et al. Tuberculosis (Edinb). 2015 Mar;95(2):190-6. doi: 10.1016/j.tube.2014.12.009. Epub 2015 Jan 7. Tuberculosis (Edinb). 2015. PMID: 25616954 Free PMC article.