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Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.
Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P. Petrelli F, et al. Among authors: deglon n. Mol Psychiatry. 2020 Apr;25(4):732-749. doi: 10.1038/s41380-018-0226-y. Epub 2018 Aug 20. Mol Psychiatry. 2020. PMID: 30127471 Free PMC article.
Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines.
Perriot S, Mathias A, Perriard G, Canales M, Jonkmans N, Merienne N, Meunier C, El Kassar L, Perrier AL, Laplaud DA, Schluep M, Déglon N, Du Pasquier R. Perriot S, et al. Among authors: deglon n. Stem Cell Reports. 2018 Nov 13;11(5):1199-1210. doi: 10.1016/j.stemcr.2018.09.015. Epub 2018 Oct 25. Stem Cell Reports. 2018. PMID: 30409508 Free PMC article.
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease.
Richetin K, Steullet P, Pachoud M, Perbet R, Parietti E, Maheswaran M, Eddarkaoui S, Bégard S, Pythoud C, Rey M, Caillierez R, Q Do K, Halliez S, Bezzi P, Buée L, Leuba G, Colin M, Toni N, Déglon N. Richetin K, et al. Among authors: deglon n. Nat Neurosci. 2020 Dec;23(12):1567-1579. doi: 10.1038/s41593-020-00728-x. Epub 2020 Nov 9. Nat Neurosci. 2020. PMID: 33169029
The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes.
Merienne N, Vachey G, de Longprez L, Meunier C, Zimmer V, Perriard G, Canales M, Mathias A, Herrgott L, Beltraminelli T, Maulet A, Dequesne T, Pythoud C, Rey M, Pellerin L, Brouillet E, Perrier AL, du Pasquier R, Déglon N. Merienne N, et al. Among authors: deglon n. Cell Rep. 2017 Sep 19;20(12):2980-2991. doi: 10.1016/j.celrep.2017.08.075. Cell Rep. 2017. PMID: 28930690 Free article.
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation.
Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, Jakobsson J. Pircs K, et al. Among authors: deglon n. Cell Rep. 2018 Aug 7;24(6):1397-1406. doi: 10.1016/j.celrep.2018.07.017. Cell Rep. 2018. PMID: 30089251 Free article.
A New Tool for In Vivo Study of Astrocyte Connexin 43 in Brain.
Droguerre M, Tsurugizawa T, Duchêne A, Portal B, Guiard BP, Déglon N, Rouach N, Hamon M, Mouthon F, Ciobanu L, Charvériat M. Droguerre M, et al. Among authors: deglon n. Sci Rep. 2019 Dec 4;9(1):18292. doi: 10.1038/s41598-019-54858-9. Sci Rep. 2019. PMID: 31797899 Free PMC article.
164 results